24-25 November 2016
National Centre for Synchrotron Science
Australia/Melbourne timezone
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Displaying 138 contributions out of 138
Type: Poster Session: Concurrent Session 3: Industry & Innovation
Track: Imaging
**Background:** Diffusion Tensor Imaging (DTI) is a popular technique used to study collagen fibre architecture in articular cartilage. Interpretation of DTI images, however, is limited to the predominant alignment of fibres only[1]. Dispersion of fibre orientations can be measured using Small angle X-ray scattering (SAXS). Here, we present a comparison of SAXS and DTI measurements in cartilage. W ... More
Presented by Mrs. Sirisha TADIMALLA
Type: Oral Session: Concurrent Session 4: Radiotherapy II
Track: Radiotherapy
Microbeam radiation therapy (MRT), using X-rays from a synchrotron, is a novel, preclinical form of radiotherapy that shows promise of providing a major advance in cancer control if successfully translated to clinical practice (Brauer-Krisch et al, 2010; Crosbie et al, 2010). Clinical translation of MRT requires developing a protocol for a patient positioning system (PPS). Following recent develop ... More
Presented by Mr. Micah BARNES on 25 Nov 2016 at 14:00
Type: Oral Session: Concurrent Session 3: Imaging - Sponsored by MASSIVE
Track: Imaging
Acid soils comprise ca. 4 billion ha of the global ice-free land or ca. 40 % of the world’s arable land. In these acid soils, the elevated solubility of Al-containing minerals results in increased concentrations of Al in the soil solution. Soluble Al is highly toxic to root growth, reducing elongation of roots in as little as 5 min due to an inhibition of wall loosening as required for cell elon ... More
Presented by Dr. Peter KOPITTKE on 25 Nov 2016 at 12:00
Type: Poster Session: Concurrent Session 4: Structural Biology II - Sponosred by DECTRIS
Track: Radiotherapy
Microbeam Radiation Therapy (MRT) is a promising preclinical radiotherapy modality that uses micron-sized, spatially fractionated radiation fields to treat radioresistant and otherwise untreatable tumours. A typical MRT configuration consists of arrays of 25-75 µm wide high-dose 'peaks' separated by 100-400 µm wide low-dose 'valleys' that are produced by an x-ray spectrum from a synchrotron ligh ... More
Presented by Mr. Matthew CAMERON
Type: Poster Track: Advanced Materials
Ovine leather has around half the strength of bovine leather and is therefore not suitable for high value applications such as shoes. For leather from a variety of animals it has been found that the extent of collagen fibril alignment (orientation index) is closely correlated with the strength of the leather. We tested whether biaxial stretching for the duration of tanning or compressing pickled p ... More
Presented by Ms. Susyn KELLY
Type: Poster Track: Technique Development
The Soft X-Ray beamline is in the process of developing a High Vacuum Automated NEXAFS chamber. To this end we have started developing automated methods for collecting NXAFS data on our existing end station. This presentation will describe the latest automated procedures that we have implemented and tested as well as what is yet to come. It is envisioned that many of the automated procedures that ... More
Presented by Dr. Lars THOMSEN
Type: Poster Track: Earth and Environment
Beachrock is produced through the lithification of sediments in the intertidal zone of tropical beaches on both continental coastlines and sand cays in reef environments. Beachrock formation through carbonate cement precipitation has the capacity to slow sea-level rise induced erosion of sand cays, islands that host vulnerable habitats, including inhabited cays and sea turtle rookeries. Beachrock ... More
Presented by Ms. Jenine MCCUTCHEON
Type: Oral Session: Concurrent Session 2: Advanced Materials II
Track: Advanced Materials
Collagen is the main structural component of many natural materials including leather and surgical scaffold materials derived from skin, and heart valve leaflets derived from pericardium. Strength is one of the key characteristics required for the application of these materials however the basis for strength in these materials is not fully understood. We have used small angle X-ray scattering in c ... More
Presented by Ms. Hannah WELLS on 24 Nov 2016 at 14:15
Type: Oral Session: Concurrent Session 2: Advanced Materials II
Track: Advanced Materials
Proteins and peptides represent the fastest growing class of pharmaceuticals with application as drugs, vaccines and diagnostics. However, they present significant challenges for drug delivery due to their complexity and fragile nature. Hybrid protein-lipid materials are highly prospective bionanomaterials for the long-term storage and controlled release of therapeutic proteins and peptides. Th ... More
Presented by Dr. Charlotte CONN on 24 Nov 2016 at 13:30
Type: Oral Session: Concurrent Session 3: Radiotherapy I
Track: Radiotherapy
In 2012, J. Boone proposed the external-beam kilovoltage radiotherapy of the breast cancer with a dedicated setup adopting an orthovoltage X-ray tube [1] rotating in full circles around the breast, with the woman in prone position. For comparison, conventional radiotherapy for breast cancer adopts a medical linac irradiating the breast with tangential beams, in supine position: the megavoltage X-r ... More
Presented by Francesca DI LILLO on 25 Nov 2016 at 11:45
Type: Oral Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Structural Biology
The macromolecular (MX) beamlines at the Australian synchrotron are mixed use between the structural biology and chemical crystallography (CX) communities. Since commissioning the high throughput MX1 bending magnet and the MX2 microfocus undulator beamlines have proven very successful for both communities. With the transfer of the Australian Synchrotron under ANSTO as recognition as its import ... More
Presented by Dr. Jason PRICE on 24 Nov 2016 at 14:30
Type: Oral Session: Concurrent Session 2: Advanced Materials II
Track: Advanced Materials
Chiral metal-organic materials, either infinite coordination polymers or discrete cages/capsules, are areas of considerable research interest due to their potential to act as catalysts for enantioselective reactions or agents to separate and purify racemic mixtures. Towards these ends, we have recently been investigating a series of enantiopure dicarboxylate ligands, built using diimide scaffolds ... More
Presented by Dr. David TURNER on 24 Nov 2016 at 14:00
Type: Oral Session: Concurrent Session 3: Radiotherapy I
Track: Radiotherapy
Therapeutic applications of synchrotron x-rays are becoming a reality. The first phase I/II clinical study of Synchrotron Stereotactic Radiation Therapy (SSRT), in place at the European Synchrotron Radiation Facility (ESRF) since 2012, consists of a dose escalation protocol to show the feasibility and safety of the technique. 13 patients have been treated using 80 keV high-flux quasi-parallel mono ... More
Presented by Dr. Jean-François ADAM on 25 Nov 2016 at 11:00
Type: Oral Session: Concurrent Session 4: Technique Development
Track: Technique Development
Small angle X-ray scattering (SAXS) is an extremely useful tool for analysing protein structures that is becoming increasingly popular. SAXS displays a number of advantages over other techniques, but radiation damage and sample consumption limit the utility of the technique to the wider protein community. Of the various avenues being pursued to circumvent radiation damage, we have focused on th ... More
Presented by Dr. Nigel KIRBY, Dr. Tim RYAN on 25 Nov 2016 at 14:15
Type: Oral Session: Concurrent Session 4: Structural Biology II - Sponosred by DECTRIS
Track: Structural Biology
Multiple drug resistance (MDR) in Gram-negative bacteria represents one of the most intractable problems facing modern medicine. Colistin and polymyxin are cationic antimicrobial peptide antibiotics which permeabilise the bacterial outer membrane and have been used to treat infections. Resistance to these antibiotics is conferred by the modification of the lipid A headgroups with phosphoethanolami ... More
Presented by Prof. Alice VRIELINK on 25 Nov 2016 at 14:45
Type: Poster Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Biological Systems
Fourier transform infrared (FTIR) spectroscopy is a well-established technique for the analysis of dairy products due to its ability to rapidly provide molecular information related to chemical composition. Despite the widespread use of FTIR spectroscopy, FTIR microspectroscopy has only had limited applications in dairy products to date. Current methods of analysis of the microstructure of dairy p ... More
Presented by Ms. Anita PAX
Type: Poster Track: Technique Development
An increasingly wide variety of condensed phase studies have been successfully undertaken at the THz/Far-IR beamline over the past few years. The combination of a small, collimated, and bright synchrotron THz photons with traditional spectroscopic techniques can offer new opportunities to scientists from fields such as nanotechnology, geology, renewable energy sources, forensics, biology, engineer ... More
Presented by Dr. Dominique APPADOO
Type: Poster Track: Advanced Materials
A series of chiral coordination cage complexes has been synthesised using amino acid substituted diimide ligands. Using a biphenylsulfonediimide core (BPSD) substituted with amino acids, a series of quadruple stranded Cu4L4 cages have been formed. The cages contain two copper paddlewheel units connected by four ligands. Analogous chiral complexes (helicates) and achiral complexes (mesocates) can b ... More
Presented by Ms. Stephanie BOER
Type: Oral Session: Concurrent Session 2: Surfaces
Track: Surfaces
In thin films of semiconductor polymers, the polymer chains often exhibit distinct orientation with respect to the substrate. The planar π-face of the backbone typically orients either in an edge-on or face-on manner. Generally, an edge-on alignment is thought to be favourable for transport in thin film transistors, whereas face-on alignment is considered to improve vertical transport as desire ... More
Presented by Chris MCNEILL on 24 Nov 2016 at 14:00
Type: Poster Track: Advanced Materials
By directly incorporating amine functionality into the ligand, the adsorption of CO2 into porous coordination polymers has been shown to be increased in comparison to the unfunctionalised frameworks. Using small polyamines such as diethylenetriamine and 1,4-bis(aminomethyl)benzene to synthesise the ligands N,Nʺ-(4-carboxybenzyl)-N,N′,Nʺ-(carboxymethyl)-diethylenetriamine (H5L1) and N,N′-di(4 ... More
Presented by Mr. Adrian EMERSON
Type: Oral Session: Plenary 1
Track: Plenary
In Structural Cell Biology detailed structural and functional descriptions of the different cellular components must be correlated with a topological map of these components at the whole cellular level. Cryo soft X-ray nanotomography (cryo-SXT) is a new complementary approach in this field that can provide information at 50 nm (full-pitch) 3D resolution of the organelle organization in whole, uns ... More
Presented by Dr. Eva PEREIRO on 23 Nov 2016 at 09:20
Type: Poster Track: Advanced Materials
Diffraction is a standard technique to study crystal structure, alignment, texture and grain structure in hard matter. The important role of neutron diffraction in (hard) materials has been cemented by the penetrative and non-ionising nature of neutrons allowing non-destructive measurements in quite unusual sample environments, the sensitivity of neutrons to thermal motions, and the opportunities ... More
Presented by Dr. Chris GARVEY
Type: Oral Session: Concurrent Session 4: Radiotherapy II
Track: Radiotherapy
Microbeam radiotherapy (MRT) was proposed as a novel RT paradigm for treating cancer some time ago. However, progress has been slow and it is unclear when or if human cancers will be treated with synchrotron radiation. There are numerous biological, medical, technical, regulatory and ethical issues to consider before a human is subjected to synchrotron MRT. This talk will give an overview of the ... More
Presented by Prof. Peter ROGERS on 25 Nov 2016 at 13:30
Type: Oral Session: Concurrent Session 1: Advanced Materials I
Track: Advanced Materials
Global energy concerns motivate the development of new and improved technologies for solar energy capture, with semiconductor photocatalysis expected to make an important contribution towards satisfying the energy needs of future societies. This talk will overview some of our recent research aimed at photocatalyst development for H2 production in alcohol-water mixtures, focussing primarily on tran ... More
Presented by Dr. Geoff WATERHOUSE on 24 Nov 2016 at 12:15
Type: Oral Session: Concurrent Session 2: Surfaces
Track: Surfaces
Diamonds exhibit remarkable properties at the confluence of biological and quantum sciences. The crystalline carbon lattice of this material acts as both a quantum vacuum, allowing long lived coherent states at room temperature, while also presenting a bio-friendly interface. Point defects in this material are now being used for an ever expanding array of quantum information and sensing applicatio ... More
Presented by Dr. Alastair STACEY on 24 Nov 2016 at 13:30
Type: Oral Session: Concurrent Session 3: Radiotherapy I
Track: Radiotherapy
Background: Diffuse Intrinsic Pontine Glioma (DIPG) is a devastating paediatric brainstem tumour with extremely poor prognosis and limited treatment options. Radiotherapy is the mainstay treatment but is limited to palliative use. Microbeam Radiotherapy (MRT) is a promising pre-clinical synchrotron radiotherapy modality which could improve the therapeutic ratio between normal tissue toxicity and t ... More
Presented by Mr. Lloyd SMYTH on 25 Nov 2016 at 11:30
Presented by Dr. Robert ACRES
Type: Poster Track: Imaging
The behaviour of gases in coal is critical to processes affecting both coal seam gas extraction and carbon sequestration. These depend on the affinity of different gases for coal and the effect they have on the coal itself when adsorbed, such as causing the coal to swell. Dynamic micro-CT offers the possibility of observing these processes on the microscopic scale as they are happening. Here we ... More
Presented by Dr. Sherry MAYO
Type: Poster Track: Advanced Materials
The photovoltaic properties of a series of diketopyrrolo[3,4-c]pyrrole (DPP) copolymers containing 3,4-ethylenedioxythiophene (EDOT) as a comonomer are reported. With use of different aryl flanking units on the DPP core, namely thiophene, pyridine or phenyl, optical gaps ranging from 1.91 eV to 1.13 eV are achieved. When blended with the fullerene derivative [6,6]-phenyl C71- butyric acid meth ... More
Presented by Mr. chao WANG
Type: Oral Session: Concurrent Session 2: Advanced Materials II
Track: Advanced Materials
The interaction between a solvent and semiconducting polymer plays a fundamental role in the formation of thin-films that are used to fabricate solution processed organic electronic devices. Depending on this interaction, polymer chains form different aggregates in a solvent that affects film morphology and in turn, charge transport properties. To realise efficient charge transport in an organic f ... More
Presented by Mr. Masrur Morshed NAHID on 24 Nov 2016 at 14:45
Type: Oral Session: Concurrent Sessions 1: Biological Systems
Track: Biological Systems
Most of the dietary calcium in milk is contained within casein micelles as so-called ‘colloidal calcium phosphate’ (CCP) nanoclusters around 2-3 nm in size. Small-angle X-ray and neutron scattering (SAXS and SANS) have been used for several decades to study the internal structure of bovine casein micelles, but there is lingering controversy over the interpretation of the scattering data [1]. ... More
Presented by Dr. Bridget INGHAM on 24 Nov 2016 at 12:00
Type: Poster Track: Imaging
Here we present x-ray imaging experiments based on the use of Ross filter pairs. Although such Ross filter arrangements have been applied in proof-of-principle spectroscopy experiments, to date there have been no reports of this approach used for full-field x-ray imaging. Here we report on the experimental demonstration of Ross filter pairs being used for quasi-monochromatic, full-field imaging in ... More
Presented by Dr. Benedicta ARHATARI
Type: Oral Session: Concurrent Session 3: Imaging - Sponsored by MASSIVE
Track: Imaging
Before birth the fetal lungs are filled with liquid, which must be cleared at birth to allow entry of air and onset of gas exchange. The rate of preterm birth and non-labour caesarean delivery has substantially increased, which delays lung liquid clearance and increases the risk of neonatal respiratory complications. Retention of liquid in airways and/or lung tissue is thought to underpin the resp ... More
Presented by Dr. Erin MCGILLICK on 25 Nov 2016 at 11:45
Type: Oral Session: Concurrent Session 1: Advanced Materials I
Track: Advanced Materials
One of the greatest challenges of the 21st century will be securing cheap and renewable sources of energy. One of the most promising approaches to this challenge is to design catalysts from earth abundant materials capable of implementing key chemical reactions including the splitting water into hydrogen and oxygen (H2O → H2 + ½O2); the oxidation of hydrogen (H2→ 2H+) and reduction (2H+→ H ... More
Presented by Rosalie HOCKING on 23 Nov 2016 at 10:30
Type: Poster Track: Advanced Materials
Metal oxides are amongst the best known and most extensively studied water oxidation catalysts. Many metal oxide materials function best in a proton accepting electrolyte such as a borate or phosphate buffer. The inclusion of these electrolyte anions in the bulk material (in small amounts) is recognized to result in amorphous metal oxides with “molecular-like” structure. The importance of thes ... More
Presented by Ms. Hannah KING
Type: Poster Track: Technique Development
It is shown that an extensive set of absolute ionisation-chamber (IC) measurements with a primary polychromatic synchrotron X-ray beam and various filter combinations/ thicknesses can be used to quite effectively estimate the flux distribution. The basic technique is simple but the “inversion” of the raw data to extract the flux distribution is fundamentally ill-posed. We demonstrate, using ... More
Presented by Dr. Andrew STEVENSON
Type: Oral Session: Concurrent Session 1: Advanced Materials I
Track: Advanced Materials
Spin Crossover (SCO) is a phenomenon where a 3d4-7 metal ion reversibly switches between two electronic states, namely high spin (HS) and low spin (LS), under an external perturbation, such as temperature, pressure or light irradiation.[1] SCO behaviour is driven by short- and long-range lattice interactions which enables spin state cooperative propagation throughout the material, resulting in hys ... More
Presented by Dr. Suzanne NEVILLE on 24 Nov 2016 at 11:45
Type: Oral Session: Concurrent Session 3: Imaging - Sponsored by MASSIVE
Track: Imaging
The Imaging and Medical Beamline (IMBL) of the Australian Synchrotron is recognised as one of the most advanced facility for the Computed Tomography (CT) experiment. It was designed for the macro-imaging, just touching the microscopy ranges in the highest magnification configuration. This design assumes that the beamline must be capable of imaging large objects up to 50cm wide. The monochromatic b ... More
Presented by Dr. Anton MAKSIMENKO on 25 Nov 2016 at 12:15
Type: Oral Session: Concurrent Session 3: Industry & Innovation
Track: Industry
Swinburne’s Factory of the Future is located in the recently opened $100 million Advanced Manufacturing and Design Centre at the university’s main campus in Melbourne, Australia. The Factory of the Future is one of three pillars of Swinburne’s newly launched Innovation Precinct which emphasises design and digital technologies to tackle manufacturing challenges, and pilot production and fabri ... More
Presented by Prof. Bronwyn FOX on 25 Nov 2016 at 11:30
Type: Oral Session: Concurrent Session 1: Earth & Environment
Track: Earth and Environment
Titan is Saturn’s largest moon and is the only planetary body in our solar system with a dense atmosphere that is comparable to Earth. Photochemical processing of the two major atmospheric components (N2 and CH4) produce a suite of hydrocarbon and nitrile species, from small hydrocarbons to large complex organic molecules (COMs) and polymeric nitriles (tholins). Tholins aggregate and coagulate t ... More
Presented by Ms. Rebecca AUCHETTL on 24 Nov 2016 at 11:30
Type: Poster Track: Earth and Environment
Fe K-edge XANES was conducted on a suite of synthetic basaltic glasses on both the XAS beamline and the XFM beamline using the Maia detector. The results will be compared.
Presented by Dr. Jeremy WYKES
Type: Oral Session: Concurrent Session 4: Technique Development
Track: Technique Development
The Macquarie University-Australian Synchrotron D-DIA apparatus is a large-volume solid-media apparatus for high pressure, high temperature in-situ x-ray experiments. The apparatus can subject a sample volume of up to 5 mm^3 to pressures to 6 GPa and temperatures to 1500 °C. During 2016/2 initial experiments were conducted on the XAS beamline. Uranium and Thorium L3-edge transmission XANES sp ... More
Presented by Dr. Jeremy WYKES on 25 Nov 2016 at 14:00
Type: Poster Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Advanced Materials
All-polymer solar cells employ an electron deficient conjugated polymer as an acceptor in lieu of the ubiquitous fullerene acceptor. All-polymer solar cells have seen a steady rise in efficiency over the past few years going from about 2% to 8.3% with the development of new donor and acceptor polymers. All-polymer solar cells have certain advantages over their fullerene counter parts in terms of t ... More
Presented by Mr. Kedar DESHMUKH
Type: Poster Track: Technique Development
GeoPIXE is the primary X-ray fluorescence analysis software used at the XFM beamline. Several new developments in GeoPIXE will be outlined, such as fitting for multiple sample matrix phases. Information will be given regarding a GeoPIXE workshop planned for 2017. User input for workshop topics is welcomed.
Presented by Dr. Daryl HOWARD
Type: Oral Session: Concurrent Session 4: Structural Biology II - Sponosred by DECTRIS
Track: Structural Biology
The advent of the Eiger family of detectors has pushed the speed of MX experiments to new heights with SAD phasing datasets being collected in as little as 1 second. The Eiger16M can produce 10Tb of data per day at a bandwidth of 40Gb/s. These high data rates come with a range of benefits and challenges for synchrotron facilities. With an Eiger 16M detector scheduled for delivery in December 2016 ... More
Presented by Tom CARADOC-DAVIES on 25 Nov 2016 at 15:00
Type: Oral Session: Concurrent Session 4: Radiotherapy II
Track: Radiotherapy
Detectors using diamond for the active layer are becoming more popular in radiotherapy because they have a relatively flat energy response and can be small. Recently published modelling of a new solid-state diamond detector (PTW model 60019) suggests that only a region of diameter 0.6 mm responds to radiation. The manufacturer’s specifications indicate that the active area is a disk of diameter ... More
Presented by Dr. Duncan BUTLER on 25 Nov 2016 at 14:30
Type: Oral Session: Concurrent Session 4: Technique Development
Track: Technique Development
Richly detailed high definition elemental images are routinely collected during experiments at the X-ray Fluorescence Microscopy (XFM) beamline [1]. In addition, complex 3D data sets may be collected - X-ray fluorescence tomography and/or XANES image stacks. For many experiments there can be up to ¼ TB of raw data to process from a 3 to 4 day visit. This presentation will describe the lates ... More
Presented by David PATERSON on 25 Nov 2016 at 15:00
Type: Poster Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Biological Systems
Hybrid protein-lipid materials such as cubosomes are a novel way to encapsulate and protect proteins for a range of nanobiotechnological applications. Peptides and proteins used in new and exciting drug applications may degrade when introduced to the human blood stream, or undergo attack by the immune system. Therefor a biologically stable and safe compound such as a lipid based cubosomes are need ... More
Presented by Mr. Jamie STRACHAN
Type: Poster Session: Concurrent Session 3: Industry & Innovation
Track: Imaging
The Imaging and Medical Beamline (IMBL) has extensive facilities for holding, preparing and performing imaging and radiotherapy experiments with animals. Animal held and/or prepared to date - Mice, rats, rabbits, sheep and a piglets. Animal care - The IMBL team includes a veterinary surgeon and we can provide excellent support to our users with anesthetics, surgery and animal care pr ... More
Presented by Daniel HAUSERMANN
Type: Poster Track: Technique Development
The fast orbit feedback system in development at the Australian Synchrotron aims to improve the stability of the electron beam by reducing the impact of moving insertion devices and targeting orbit perturbations at the mains frequency (50 Hz, 100 Hz and 300 Hz). The feedback system is designed to have a unity gain at a frequency greater than 300 Hz using a PI controller with harmonic suppressors i ... More
Presented by Mr. Greg LEBLANC
Type: Poster Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Biological Systems
Dilek Yalcin Tuncalia, Radhika Mohandassa, Calum J Drummonda, Tamar L Greavesa a School of Science, College of Science, Engineering and Health, RMIT University, GPO Box 2476, Melbourne, Victoria 3001, Australia Protic ionic liquids (PILs) are increasingly being used as solvents for biological molecules due to their desirable properties. Biomolecules such as amino acids, peptides and proteins ... More
Presented by Ms. Dilek YALCIN TUNCALI
Type: Oral Session: Concurrent Session 2: Advanced Materials II
Track: Advanced Materials
Organic semiconductors (OSCs) possess many inherent advantages that allow them to be used effectively as organic field effect transistors (OFETs). Solution processablility allows rapid, large area fabrication on low cost flexible substrate that make them ideal for specialized applications such as flexible displays and radio frequency identification (RFID). Small molecule OSCs provide chemical s ... More
Presented by Mr. Adam WELFORD on 24 Nov 2016 at 14:30
Type: Oral Session: Concurrent Session 2: Surfaces
Track: Surfaces
Fungi possess the ability to colonize a wide array of surfaces, including metallic surfaces; the product of colonization is the proliferation and formation of a fungal biofilm followed by the degradation and alteration of the metallic surface. In particular, microbially-induced corrosion on the surface of metals occurs due to changes in the local acidity, creating galvanic and differential aeratio ... More
Presented by Dr. Vi Khanh TRUONG on 24 Nov 2016 at 14:45
Type: Poster Track: Advanced Materials
Combining synchrotron radiation with various sample environment setups, such as capillary flow cell, we are able to understand the mechanism of gas absorption properties from MOFs and zeolites. In-situ powder X-ray diffraction (PXRD) measurements have been conducted to discover a “molecular trapdoor” mechanism for exclusive gas discrimination, which is demonstrated as an unusual operating regi ... More
Presented by Dr. Qinfen GU
Type: Oral Session: Concurrent Session 1: Advanced Materials I
Track: Advanced Materials
Titanium alloys are widely used in aerospace applications due to their unique superiority of low density and high strength. In order to optimize the performance of Ti alloy, prior knowledge of the microstructure-property relationships and microstructural evolution as a result of processing should be studied. Synchrotron radiation-based X-ray micro-computed tomography (SR µ-CT) has been develope ... More
Presented by Mr. Yuqi REN on 24 Nov 2016 at 11:00
Type: Oral Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Structural Biology
Radhika Mohandass1, Dilek Yalcin1, Calum Drummond1 Tamar Greaves1 1. School of Science, College of Science, Engineering and Health, RMIT University, Melbourne, VIC, Australia Email: s3607967@student.rmit.edu.au Ionic liquids (ILs) can have a stabilizing or destabilizing effect on proteins, which is strongly dependent on the cation and anion of the IL (1). Consequently ILs have potential to be ... More
Presented by Ms. Radhika MOHANDASS on 24 Nov 2016 at 15:00
Type: Oral Session: Concurrent Sessions 1: Biological Systems
Track: Biological Systems
Milk provides an important source of energy for children, and is one of the staple foods for adults with Western diet. The World Health Organization and the Australian government have recommended exclusive human milk feeding for infants below 6 months, although commercial infant formulas (IF) can be used as human milk substitute in circumstances where human milk is not adequate.[1,2] IF is general ... More
Presented by Dr. Malinda SALIM on 24 Nov 2016 at 12:15
Type: Poster Track: Technique Development
Free Electron Laser (FEL) facilities are capable of producing a peak brightness 10 orders of magnitude above 3rd generation light sources, with 10$^{11}$ to 10$^{13}$ photons per pulse. With ultra-fast pulse durations of 100 fs down to <10 fs, these FELs are capable of imaging structures at the molecular and atomic size level and investigating dynamical processes over timescales that take place on ... More
Presented by Tessa CHARLES
Type: Poster Track: Structural Biology
The ability to determine the progress of an experiment is critical to efficiently use beamtime during synchrotron visits. While processing results from individual datasets are sufficient for many crystallography experiments, chemical crystallography experiments that require use of the minikappa to collect datasets from multiple orientations, and sensitive samples where partial datasets can be coll ... More
Presented by Jun AISHIMA
Type: Oral Session: Concurrent Session 4: Technique Development
Track: Technique Development
Crystalline phase determination, polycrystallinity, strain, grain orientation as well as defect structure, migration and organisation are fundamental to the understanding of materials’ properties. The MMC beamline is the only facility planned for the Australian Synchrotron that will enable these properties to be spatially resolved at the micron scale. We present the current design and capa ... More
Presented by Prof. Andrea GERSON on 25 Nov 2016 at 13:30
Type: Oral Session: Concurrent Session 4: Radiotherapy II
Track: Radiotherapy
Dosimetric properties of synchrotron microbeams are extremely difficult to measure due to the small field sizes employed (typically 50 um width with 200 – 400 um peak-to-peak spacing) and must undergo rigorous validation before patient treatments can be performed on the IMBL. The radiochromic PRESAGE® dosimeter offers a unique opportunity to validate dosimetry models in 3D with similar radio ... More
Presented by Mr. Frank GAGLIARDI on 25 Nov 2016 at 14:15
Type: Oral Session: Concurrent Session 1: Earth & Environment
Track: Earth and Environment
The Saturated Fine-Grained (SFG) soil, as one type of important materials of dredger mud, is related closely to bearing capacity of foundation in consolidation progress of reclamation engineering. It is necessary to research the quantitative mechanism between micro and macro mechanics by microstructure evolution of SFG soil consolidation. However, it is difficult to obtain the 3D microstructure ch ... More
Presented by Ms. Jing SONG, Mr. Yuqi REN on 24 Nov 2016 at 11:45
Type: Oral Session: Concurrent Session 4: Structural Biology II - Sponosred by DECTRIS
Track: Structural Biology
The micro-crystallography beamline, MX2, depends on three mirror elements for conditioning and focussing the beam at the sample position. One of these, the Microfocussing Horizontally Focussing Mirror (MHFM) is showing signs of beam damage. A likely source of this damage is the high-voltage piezo bender bimorph system used to shape the mirror. This manifests as significant structure in the bea ... More
Presented by Dr. Daniel ERIKSSON on 25 Nov 2016 at 14:15
Type: Oral Session: Concurrent Sessions 1: Biological Systems
Track: Biological Systems
Our team, together with international collaborators, has been studying plants that hyperaccumulator trace elements, especially nickel, from various ecosystems around the world. The aim of these investigations has been to advance our understanding of the ecophysiology of these unusual plants. We have employed a range of micro-analytical methods to reveal the in situ distribution, biogeochemical ... More
Presented by Dr. Antony VAN DER ENT on 24 Nov 2016 at 11:00
Type: Poster Track: Technique Development
The higher and lower ends of the “Tender” X-ray region are not well defined in photon energy but the core of the range can be considered to be the point at which the two common X-ray monochromator types start to swop over; at present that swop over point is between 1.5 to 2 KeV. The two common monochromators are the double crystal monochromator (DCM) and the grating monochromator. The DCM re ... More
Presented by Bruce COWIE
Type: Poster Track: Technique Development
There is growing interest in combining soft X-ray ptychography with spectroscopy and applying it to the study of functional materials and biological systems in situ [1-3]. Realising the full potential of this method depends on efficient nanofocusing of the X-ray beam. Fresnel zone plates (FZP) are commonly employed, but their efficiency is typically less than 10% [4]. Achieving higher efficiency g ... More
Presented by Mrs. Alaleh AMINZADEH
Type: Poster Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Advanced Materials
Organic photovoltaics (OPV) have received much attention due to the promise of low-cost, efficient processing of solar cells onto flexible substrates. Typically, OPVs consist of a polymeric donor and a fullerene acceptor material, however, fullerene shortcomings such as poor light harvesting ability and high synthesis costs have resulted in the exploration of alternative acceptor materials. Small ... More
Presented by Ms. Kira RUNDEL
Type: Poster Track: Technique Development
Observing time resolved changes to weak signals has always been a challenge that the Australian Synchrotron SAXS beamline has been well placed to address. Recent work at the beamline has aimed to find the optimum sample environment and beamline setup for picking out weak signals from in-situ digestion experiments. Aided by some knowledge gained from the i22 beamline at the Diamond synchrotron in t ... More
Presented by Dr. Adrian HAWLEY
Type: Poster Session: Concurrent Session 3: Industry & Innovation
Track: Imaging
IMBL Users have a range of demands for x-ray imaging detectors which cannot be met by one single instrument. For the past four years of operation we have kept a suite of six detectors to match the foreseeable needs. As the beamline has developed in capability over time, the demands on detection have also changed. Furthermore, some of the original detectors are now getting to the end of their usefu ... More
Presented by Dr. Chris HALL
Type: Oral Session: Concurrent Sessions 1: Biological Systems
Track: Biological Systems
The hippocampus is a key anatomical brain structure required for spatial learning and memory in all mammals. The structure of the hippocampus is highly conserved between mammalian species, which highlights a fundamental importance to higher order brain function. As such, the hippocampus is one of the most studied anatomical structures in the field of neuroscience. However, much remains unknown abo ... More
Presented by Dr. Mark John HACKETT on 24 Nov 2016 at 11:45
Type: Poster Track: Advanced Materials
This work targets the development of efficient metal co-catalyst modified titania photocatalysts for alcohol photoreforming to H2 that function under direct sunlight. Conventionally, noble metals such as platinum, palladium or gold have been used co-catalysts to activate TiO2 for hydrogen production, though the use of such co-catalysts for industrial scale H2 manufacture is not feasible due to the ... More
Presented by Ms. Wan-Ting CHEN
Type: Oral Session: Concurrent Session 4: Structural Biology II - Sponosred by DECTRIS
Track: Structural Biology
We have used protein crystallography and small angle X-ray scattering to understand the way that enzymes respond to remote signals – a process known as allostery (from the Greek *allos* meaning “other” and *stereos* meaning “solid”). Allostery is critical to the control of metabolism, and although allostery has been known for many years, it is only more recently that the molecular netwo ... More
Presented by Prof. Emily PARKER on 25 Nov 2016 at 13:30
Type: Poster Session: Concurrent Session 3: Industry & Innovation
Track: Imaging
Data acquisition at virtually every beamline at the AS involves scanning; however, none more so than the XFM beamline, where every pixel in an image is acquired serially by scanning a specimen through a tightly-focused beam. At XFM, faster scanning means more science. On-the-fly scanning has significantly improved scan speeds by removing overheads between pixels. However, developments in the p ... More
Presented by Mr. Nader AFSHAR
Type: Oral Session: Concurrent Session 4: Technique Development
Track: Technique Development
This presentation gives an overview of the development and comparison of different sample preparation techniques for presenting samples to the Far-IR and IR beam line at the Australian Synchrotron. We have investigated using polyethylene (PE), polytetrafluoroethylene (PTFE), polyvinylacetate (PVA), paraffin, and mixtures, as matrixes for pellets. We have also trialled pressing pure compounds w ... More
Presented by Ms. Josie NUNN on 25 Nov 2016 at 14:45
Type: Poster Track: Imaging
The problem of optimising the experimental protocol and data analysis for in-vivo breast cancer screening was investigated using synchrotron-based in-line X-ray phase-contrast tomography. Results are presented of experiments conducted at the IMBL and SYRMEP beamlines of Australian and Elettra Synchrotrons using the propagation-based phase-contrast mammographic tomography method, which incorporates ... More
Presented by Mr. Darren THOMPSON
Type: Oral Session: Concurrent Session 3: Radiotherapy I
Track: Radiotherapy
Microbeam radiation therapy (MRT) implements spatially-fractionated kilovoltage x-rays for deep-seated tumour treatment [1,2] to provide better normal tissue sparing [3]. However, tumour treatment with MRT can be further optimized with high-Z nanoparticles (NPs), which have been shown to enhance the dose delivered by conventional radiotherapies [4]. Tantalum pentoxide (Ta2O5) NPs are novel nano-s ... More
Presented by Prof. Michael LERCH on 25 Nov 2016 at 12:15
Type: Oral Session: Concurrent Session 2: Surfaces
Track: Surfaces
Block copolymers can self-assemble into well-defined, nanoscale morphologies, which are typically isotropic and lack long range order. Chemical or physical templates generated through optical lithography can direct self assembly to create morphologies with enhanced long range order and fashion them into hierarchical patterns. This ability allows the patterns formed to be optimized to be more suita ... More
Presented by Mr. Lewis CHAMBERS on 24 Nov 2016 at 15:00
Type: Oral Session: Concurrent Session 1: Advanced Materials I
Track: Advanced Materials
We have studied the long-range average and short-range local structures in Y2Ti2-xHfxO7 (x = 0-2.0) using diffraction and spectroscopy techniques respectively. Both neutron and synchrotron X-ray powder diffraction data show a clear phase transition of the average structure from ordered pyrochlore to disordered defect-fluorite at x ~ 1.6; the long-range anion disorder appears to develop gradually ... More
Presented by Dr. Zhaoming ZHANG on 24 Nov 2016 at 11:30
Type: Oral Session: Concurrent Session 4: Radiotherapy II
Track: Radiotherapy
There are currently two biomedical synchrotron beamlines in the world with an MRT program and an active MRT user base: ID17 at the European Synchrotron Radiation Facility (ESRF), France, and the Australian Synchrotron’s Imaging and Medical Beamline (IMBL). The European program has been ongoing since the 1990s and has identified radioresistant brain tumours as a clinical target for MRT. Indeed, m ... More
Presented by Dr. Jayde LIVINGSTONE on 25 Nov 2016 at 14:45
Type: Poster Track: Technique Development
The Australian Synchrotron storage ring has achieved a world record low vertical emittance below 1 pm rad. These beam parameters produce very small beam sizes which are hard to accurately measure. This proposal is to test an Young's Double slit X-ray interferometer on the long baseline of the IMBL to measure vertical electron beam sizes down to 1.6 $\mu$m. These measurements will be part of the ve ... More
Presented by Dr. Mark BOLAND
Type: Poster Track: Imaging
Rodent models of allergic airways disease largely replicate the pathophysiology of asthma and are widely used in basic science and in preclinical drug evaluation.The phenotype of allergic airways disease rodents with a genetic deficiency or their response to pharmacological treatment can be assessed according to clinically relevant endpoints including lung function tests.This often takes the form ... More
Presented by Dr. Simon ROYCE
Type: Poster Session: Concurrent Session 3: Industry & Innovation
Track: Imaging
Rodent models of allergic airways disease largely replicate the pathophysiology of asthma and are widely used in basic science and in preclinical drug evaluation. The phenotype of allergic airways disease rodents with a genetic deficiency or their response to pharmacological treatment can be assessed according to clinically relevant endpoints including lung function tests. This often takes the f ... More
Presented by Dr. Simon ROYCE
Type: Oral Session: Concurrent Session 3: Imaging - Sponsored by MASSIVE
Track: Imaging
Studies of ore systems require microanalysis of samples to gather information on mineral chemistry. Information from in-situ microcharacterisation studies can be used both to recognise mineral zonations and chemical relationships among mineral phases that provide a record of hydrothermal activity, fluid chemistry and fluid-rock reactions. Such information is vital in constraining the physio-chemic ... More
Presented by Dr. Louise FISHER on 25 Nov 2016 at 11:00
Type: Oral Session: Concurrent Session 1: Earth & Environment
Track: Earth and Environment
The radiological residues at the former weapons testing sites in Australia, at Maralinga, Emu and the Monte Bello Islands, often occur in particulate form (“hot particles”). Large numbers of these particles were emitted from nuclear test detonations and non-nuclear tests. For example, more than 3000 readily identifiable particles can occur in the soil of a single square meter, in a plume that ... More
Presented by Mr. David CHILD on 24 Nov 2016 at 11:15
Type: Poster Track: Advanced Materials
Rare earth 4-(4’-methylpenyl)-4-oxo-butanoate, (L) complexes [RE(L)3(H2O)] (RE = Y, La, Ce, Nd, Ho, Er) have been prepared by metathesis reactions between the corresponding rare earth chloride and NaL to assess the potentiality as new corrosion inhibitors. The products were analysed by IR- and NMR-spectroscopy, elemental- and metal analysis and TGA measurements. The single crystal X-ray diffrac ... More
Presented by Mr. Oliver HEILMANN
Type: Poster Track: Technique Development
Highly collimated synchrotron-IR beam offers 100-1000 times higher brightness than that of internal IR source used in laboratory-based FTIR instruments, enabling acquisition of high-quality FTIR spectra at diffraction-limited spatial resolution. Such properties make synchrotron-IR an excellent analytical platform for acquiring spatially resolved chemical “mapping” of materials at lateral resol ... More
Presented by Dr. Jitraporn (Pimm) VONGSVIVUT
Type: Oral Session: Concurrent Sessions 1: Biological Systems
Track: Biological Systems
Biological applications which utilise enzymes, or other proteins, require the tertiary structure of the protein to be retained. However, many proteins readily undergo aggregation or denaturation when outside their native environment, and/or over longer timescales. The stability of proteins in solvents other than water is usually considered unappealing due to an assumption that the protein will be ... More
Presented by Dr. Tamar GREAVES on 24 Nov 2016 at 11:15
Type: Oral Session: Concurrent Session 1: Advanced Materials I
Track: Advanced Materials
X-ray micro-beam Laue diffraction is a powerful tool for mapping the orientation and elastic strain within polycrystalline materials. Interactions between neighbouring grains influence the macroscale characteristics of a material, particularly its deformation behaviour, damage initiation and propagation mechanisms. Here we report on recent experiments using energy scanning diffraction of a polycry ... More
Presented by Mr. Henry KIRKWOOD on 24 Nov 2016 at 12:00
Type: Poster Track: Advanced Materials
Modern hard drive disks (HDDs) store information in the form of magnetic field orientation combinations. Information density / size of HDDS are hence limited by the size of the magnets used to construct the device. Molecules and single ions capable of magnetic hysteresis, termed single molecule magnets (SMMs) and single ion magnets (SIMs), respectively, are of interest then as a means to miniaturi ... More
Presented by Mr. Owen BEAUMONT
Type: Oral Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Structural Biology
The assembly and regulation of viral capsid proteins into highly ordered macromolecular complexes is essential for viral replication. Recent reports have elucidated the ability of capsids to switch between T1 and T3 symmetry, however little is known regarding how capsid proteins can switch between smaller, non-icosahedral macromolecular complexes. Here we utilize crystal structures of the capsid p ... More
Presented by Jade FORWOOD on 24 Nov 2016 at 14:45
Type: Oral Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Structural Biology
Structural Maintenance of Chromosomes flexible Hinge Domain-containing 1 (SMCHD1) is a non-canonical SMC protein that plays critical roles in epigenetic regulation. Recently, heterozygous loss of function mutations in *SMCHD1* were identified in facioscapulohumeral muscular dystrophy (FSHD) patients, leading to failure of epigenetic silencing of the disease-causing gene *DUX4* in muscle cells. Whi ... More
Presented by Dr. Kelan CHEN on 24 Nov 2016 at 14:00
Type: Oral Session: Concurrent Session 4: Structural Biology II - Sponosred by DECTRIS
Track: Structural Biology
Understanding the process of invasion is essential for developing strategies to stop blood stage infection. An important feature of *Plasmodium* invasion is the host cell selectivity that the different species have for cells of the erythroid lineage. Indeed, *Plasmodium vivax* preferentially invades reticulocytes which are immature red blood cells. Several members of *P. vivax* Reticulocyte Bindin ... More
Presented by Dr. Jakub GRUSZCZYK on 25 Nov 2016 at 14:30
Type: Oral Session: Concurrent Sessions 1: Biological Systems
Track: Biological Systems
Èlastin is a highly elastic protein found in connective tissue of vertebrates. It has an important mechanical physiological function by virtue of its highly elastic nature, namely to provide recoil in tissue such as skin and vasculature. The structure is extremely stable being produced mainly early in life where it persists and is not replaced during a lifetime. The structure and mechanical prope ... More
Presented by Dr. Christopher GARVEY on 24 Nov 2016 at 11:30
Type: Oral Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Structural Biology
Ezrin is member of the ERM (Ezrin-Radixin-Moesin) family of proteins that have been conserved through metazoan evolution. These proteins have dormant and active forms, where the latter links the actin cytoskeleton to membranes. ERM proteins have three domains: an N-terminal FERM (band Four-point-one ERM) domain comprising three subdomains (F1, F2 and F3); a helical domain; and a C-terminal actin-b ... More
Presented by Dr. Anthony DUFF on 24 Nov 2016 at 14:15
Type: Poster Track: Structural Biology
Plasmin is essential for a number of physiological functions including fibrinolysis, tissue remodelling and wound healing. The conversion of the zymogenic plasminogen to its active, serine protease form, is an important molecular event that regulates the timely delivery of active plasmin at the critical locations as required. Furthermore, binding of plasminogen to cell surface receptors promot ... More
Presented by Mr. Blake MAZZITELLI
Type: Oral Session: Concurrent Session 2: Advanced Materials II
Track: Advanced Materials
Colloidal suspensions of hard spheres are valuable experimental model systems for exploring phase behaviour and dynamics in condensed matter. Such colloids form colloidal crystals at concentrations above the freezing volume fraction of 0.494, allowing the investigation of the kinetics and dynamics of crystallization. As colloidal particles are much bigger than atoms, processes are correspondingly ... More
Presented by Prof. Gary BRYANT on 24 Nov 2016 at 15:00
Type: Poster Track: Advanced Materials
A family of Fe(II) spin crossover complexes with halogen substituted 5-X-N-(8-quinolyl)salicylaldimines (HqsalX, X = F 1, Cl 2, Br 3 and I 4) has been investigated. With N4O2 octahedral environments, a somewhat unusual donor system for Fe(II) spin crossover [1], this is the first time that [Fe(II)(qsal-X)2] complexes have been studied [2]. Compounds 2, 3 and 4 unexpectedly show completed abrupt sp ... More
Presented by Dr. Wasinee PHONSRI
Type: Poster Track: Earth and Environment
We described a synchrotron Fourier transform infrared (IR) microscope method to characterize fouling layer. Combined fouling with organic foulant and colloidal silica in membrane distillation (MD) was used as an example. The synchrotron IR mapping was capable of revealing the spatial distribution of foulants as well as chemical information of foulant-membrane interface. Our results showed that syn ... More
Presented by Dr. Ming XIE
Type: Oral Session: Concurrent Session 3: Industry & Innovation
Track: Industry
This presentation will provide an overview of industrial studies using synchrotron-based techniques undertaken over the past 20+ years by the presenter. The objective is to provide perspective on the wide scope of possible applications and motivations for industry participation. These applications focus mainly on minerals and materials studies and have included: • wax crystallisation from dies ... More
Presented by Prof. Andrea GERSON on 25 Nov 2016 at 11:45
Type: Oral Session: Concurrent Session 3: Radiotherapy I
Track: Radiotherapy
Discovery of the radiation-induced bystander effect (RIBE) demonstrates that cell death and genomic instability are not restricted to cells that are directly exposed to ionising radiation. The RIBE refers to a situation where cells that have not been directly exposed to IR behave as though they have been exposed. This phenomenon presents real clinical consequences such as increased risk of seconda ... More
Presented by Mrs. Jessica VENTURA on 25 Nov 2016 at 12:00
Type: Poster Track: Advanced Materials
The Haverkamp research group at Massey University (NZ), scientists at the Australian Synchrotron, and a number of international companies are collaborating on several research projects into collagen materials using small angle X-ray scattering (SAXS). The research advances basic knowledge by revealing the structural basis of physical properties, boosts understanding which improves industrial proce ... More
Presented by Ms. Susyn KELLY
Type: Oral Session: Concurrent Session 1: Earth & Environment
Track: Earth and Environment
Synchrotron Radiation-based X-ray Micro-Computed Tomography (SR-µCT) is a leading edge technology allowing unprecedented grain-scale observations helping with a better understanding of geomaterial behavior. The higher energy level used in this technique allows rapid scanning of geomaterials under high stress levels to study the progress of crushing and crack propagation. This paper demonstrates a ... More
Presented by Dr. Mahdi DISFANI, Dr. Guillermo NARSILIO on 24 Nov 2016 at 12:15
Type: Oral Session: Concurrent Session 3: Imaging - Sponsored by MASSIVE
Track: Imaging
This study was conducted on a human aorta phantom with a commercially available stent graft placed in the aorta with the aim of investigating visualization of aortic stent graft by synchrotron radiation. Synchrotron tomography experiments were performed on imaging and medical beamline at the Australian Synchrotron facility, with beam energy ranging from 40 to 100 keV, with spatial resolution of 19 ... More
Presented by Prof. Zhonghua SUN on 25 Nov 2016 at 11:30
Type: Poster Track: Advanced Materials
Lanthanoid-8-quinolinolates and its derivatives have attracted a lot of interest due to their structures and behaviour as single molecular magnets [1-3]. A few multinuclear of lanthanoid complexes with 2-methyl-8-hydroxyquinoline (HMQ) were successfully synthesized at elevated temperature using a Teflon Sealed autoclave. It was observed that heating the mixture above the boiling point of the solve ... More
Presented by Ms. Nurul F. GHAZALI
Type: Poster Track: Advanced Materials
Syntheses of high reactivity lanthanoid organometallics (Ln-C), organoamides (Ln-NR2), and aryloxides (Ln-OAr) by redox transmetallation (RT) and redox transmetallation protolysis (RTP) reactions have been widely and successfully studied by using mercury compounds. [1] This report describes a new method to synthesize metal-organic lanthanoid derivatives by using trispentafluorophenylbismuth replac ... More
Presented by Ms. ZHIFANG GUO
Type: Poster Track: Radiotherapy
Background: Synchrotron Radiotherapy is characterised by high intensity beams which are capable of delivering dose-rates that are up to 10,000 times faster than conventional radiotherapy dose rates. Systematic normal tissue toxicity data is required in order to progress towards human clinical trials. Aim: To assess the safety profile of both Synchrotron broad-beam radiotherapy (SBBR) and Microbe ... More
Presented by Mr. Lloyd SMYTH
Type: Oral Session: Concurrent Session 1: Earth & Environment
Track: Earth and Environment
Formic acid (HCOOH) is the most abundant trace gas organic acid in the atmosphere, resulting from oxidation or photochemical processing of alkanes from biogenic and anthropogenic sources.[1] Formic acid dissolves well in water and thus contributes significantly to rain acidity in remote regions. Due to its good solubility it is believed that formic acid contributes to cloud condensation.[2] It is ... More
Presented by Mr. Mahmut RUZI on 24 Nov 2016 at 12:00
Type: Oral Session: Concurrent Session 3: Industry & Innovation
Track: Industry
One of Australia’s world class research facilities, the Australian Synchrotron, provides cutting edge tools to academic and industry researchers, empowering them to problem solve and innovate in a wide range of sectors. As well as servicing the traditional academic user base, the Australian Synchrotron has an Industry Engagement team focused on supporting commercial customers to utilise the sy ... More
Presented by Dr. Robert ACRES on 25 Nov 2016 at 11:00
Type: Oral Session: Concurrent Session 2: Surfaces
Track: Surfaces
Corrosion of metallic surfaces is prevalent and of great concern in a wide range of industries, particularly those in transport, aviation, building and food sectors, reportedly responsible for a direct cost of $276 billion per annum(1). Galvanization has been widely used as a corrosion preventative method by coating the metallic surfaces with zinc that serves as a physical barrier to prevent corro ... More
Presented by Dr. Jitraporn (Pimm) VONGSVIVUT on 24 Nov 2016 at 14:15
Type: Oral Session: Concurrent Session 4: Technique Development
Track: Technique Development
Sample positioning and rotation on the X-ray beam are critical experimental parameters for a successfully experiment . This becomes exacerbated when handling small crystals on a micro-focus beam like the one provided by the MX2 beamline at the Australian Synchrotron. Here it is paramount that the centre of rotation is on the same location as the X-ray beam. For one hand, any procession, particular ... More
Presented by Dr. David ARAGAO on 25 Nov 2016 at 14:30
Type: Poster Track: Advanced Materials
Birnessites and closely related phases of manganese oxides are catalysts for a range of chemical reactions. These include the classical chemical demonstration of the disproportionation of hydrogen peroxide, decarboxylation reactions, the oxidation of amines to imines and water oidation. Because these reactions are so different we seldom think about the selectivity of one reaction and what it mea ... More
Presented by Ms. Mayada SABRI
Type: Poster Track: Structural Biology
*Pseudomonas aeruginosa* is an opportunistic human pathogen associated with the chronic infection of the lungs of Cystic Fibrosis patients – New Zealand’s most common lethal genetic disease. *P. aeruginosa* has an innate resistance to antibiotics and concerns exist around the appearance of multi-drug resistant strains [1]. The shikimate pathway is responsible for the biosynthesis of key ar ... More
Presented by Mr. Oliver STERRITT
Presented by Dr. Jean-François ADAM on 25 Nov 2016 at 16:45
Type: Poster Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Biological Systems
Platinum(II) based anti-cancer drugs are the most successful class of chemotherapy drugs in clinical use and are used to treat half of all patients undergoing chemotherapy. Despite their success they are often associated with dose limited toxicities, severe side effects and drug resistance.[1-3] Platinum(IV) complexes are a promising class of pro-drugs which may bypass the problems associated wi ... More
Presented by Catherine CHEN
Type: Oral Session: Concurrent Session 2: Surfaces
Track: Surfaces
The second half of 2016 has seen the completion of a bespoke experiment installed at the THz/Far-IR Beamline. Funded by the ARC through CI Ennis' DECRA project, the apparatus has been designed for dual-purpose Matrix-Isolation and Reflection-Absorption Infrared Spectroscopy studies. A chamber sitting within the beamline’s Bruker FTIR sample compartment reaches high-vacuum by differential pumping ... More
Presented by Dr. Courtney ENNIS on 24 Nov 2016 at 14:30
Type: Oral Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Structural Biology
Enzymes must be ordered to allow the stabilization of transition states by their active sites, yet dynamic enough to adopt alternative conformations suited to other steps in their catalytic cycles. The biophysical principles that determine how specific protein dynamics evolve and how remote mutations affect catalytic activity are poorly understood. Here we examine a 'molecular fossil record' that ... More
Presented by Prof. Colin JACKSON on 24 Nov 2016 at 13:30
Type: Oral Session: Concurrent Sessions 1: Biological Systems
Track: Biological Systems
The shape and structure of animals is fundamental to their survival, including how they move and feed: bone shape determines how forces are transmitted from muscles during running and flying, and the microstructure of a tooth dictates whether it will break when crushing food. Our ability to adequately capture the fine-scale 3D structure of biological materials has until recently been very limited, ... More
Presented by Dr. Alistair EVANS on 23 Nov 2016 at 10:30
Type: Poster Track: Earth and Environment
Low-rank fuels such as biomass and mixed municipal solid waste (MSW) can be valorised into useful products ranging from chemicals to bio-oil through thermochemical treatment. However, disparate physical and chemical properties of these fuels entail usage of different heating rates for isolating the product of interest. Rapid thermal degradation of biomass is conducive for producing chemicals where ... More
Presented by Mr. Anurag PARIHAR, Ms. Vibhuti CHHABRA
Type: Oral Session: Concurrent Session 4: Radiotherapy II
Track: Radiotherapy
**Introduction** Synchrotron microbeam radiation therapy (MRT) is a novel radiotherapy modality with significant clinical potential. We have produced a simple dose calculation algorithm for MRT using the Eclipse Treatment Planning System (TPS), by Varian Medical Systems. **Method** The calculation engine in Eclipse was configured to directly evaluate ‘peak’ doses. Monte Carlo-simulate ... More
Presented by Mr. Liam DAY on 25 Nov 2016 at 15:00
Type: Oral Session: Plenary 2
Track: Plenary
Characterisation of tuneable and adaptive materials at the Australian Synchrotron has enabled an understanding of non-equilibrium processes such as solute partitioning and phase competition in alloys [1-6], architecturing of free volume in polymers [7-9], and biomineralisation of metal-organic-frameworks (MOFs) [10-16]. In situ small angle X-ray scattering (SAXS) and in-situ powder X-ray diffract ... More
Presented by Dr. Anita HILL on 24 Nov 2016 at 08:45
Type: Oral Session: Concurrent Session 4: Structural Biology II - Sponosred by DECTRIS
Track: Structural Biology
Autotransporter proteins are the largest group of outer membrane and secreted virulence factors from important bacterial pathogens such as Salmonella enterica, Shigella flexneri, Neisseria meningitidis and pathogenic E. coli strains. They are important contributors to bacterial pathogenesis, functioning as toxins, adhesins and facilitators of biofilm formation. Their importance to human health h ... More
Presented by Dr. Jason PAXMAN on 25 Nov 2016 at 14:00
Type: Oral Session: Concurrent Session 1: Advanced Materials I
Track: Advanced Materials
Transition metal modified titania (M/TiO2, M = Pd, Pt or Au) photocatalysts have shown excellent activity for H2 production in alcohol-water mixtures under UV excitation [1, 2]. Recently, we have found that a 0.25 wt.% Pd-0.25 wt.% Au/TiO2 photocatalyst demonstrated a superior H2 production rate of 68 mmol g-1 h-1 compared to monometallic 0.50 wt.% Pd/TiO2 (43.0 mmol g-1 h-1) or 1.00 wt.% Au/TiO2 ... More
Presented by Mr. Andrew CHAN on 24 Nov 2016 at 11:15
Type: Oral Session: Concurrent Session 1: Earth & Environment
Track: Earth and Environment
The relationship between uranium (U) and organic matter (OM) has received increasing attention in the fields of mining and remediation. Sediments and wetlands with high (%) OM content can accumulate U from groundwater, and over geological timescales lead to ore formations. The Mulga Rock deposit (13K tonnes of U) near Kalgoorlie, WA is one example in Australia, with many other examples found glob ... More
Presented by Susan CUMBERLAND on 23 Nov 2016 at 10:30
Type: Poster Track: Advanced Materials
The formation and growth of nanoparticles is of critical importance in a variety of scientific areas and in everyday life. The prevailing models used to describe these processes have mainly been based on thermodynamic arguments and by the use of concepts such as “monomers” or “particles”, thereby omitting to incorporate the important influence of differences in the chemical nature of diffe ... More
Presented by Dr. Espen BOJESEN
Type: Oral Session: Plenary 3
Track: Structural Biology
TIR (Toll/interleukin-1 receptor, resistance protein) domains are key components of innate immunity signaling pathways. They are found in animals, plants and bacteria, for example in TLRs (Toll-like receptors) and TLR adaptors in animals, NLRs (nucleotide binding, leucine-rich repeat receptors) in plants, and virulence factors interfering with immune responses in bacteria. While it has been well e ... More
Presented by Prof. Bostjan KOBE on 25 Nov 2016 at 15:15
Type: Poster Track: Technique Development
The spatial distribution of metals can provide key information for a range of studies. Metals are key to virtually every aspect of life, including health, culture, society, nutrition, and technology. This poster will outline the fundamental concepts in X-ray Fluorescence Microscopy, providing points of departure for understanding the method and its application. We actively encourage prospective ... More
Presented by Dr. Martin DE JONGE
Type: Oral Session: Concurrent Session 1: Earth & Environment
Track: Earth and Environment
Element substitution that occurs during fluid-rock interaction permits assessment of fluid composition and interaction conditions in ancient geological systems, and provides a way to fix contaminants from aqueous solutions. We conducted a series of hydrothermal mineral replacement experiments to determine whether a relationship can be established between arsenic (As) distribution in apatite and fl ... More
Presented by Dr. Weihua LIU on 24 Nov 2016 at 11:00
Type: Poster Session: Concurrent Session 2: Structural Biology I - Sponsored by DECTRIS
Track: Biological Systems
Aberrant wound healing, as observed in the presence of co-morbidities such as diabetes, represents a major clinical problem. To improve wound care, a better understanding of the cellular and molecular details of healing processes is required. Our aim was to utilize Synchrotron- and focal plane array (PFA)-based Fourier-transform infrared (FTIR) chemical mapping for further characterizing the woun ... More
Presented by Dr. Karagiannis TOM
Type: Oral Session: Concurrent Session 3: Industry & Innovation
Track: Industry
Coal is a highly complex and heterogeneous material. Certain coals will convert to coke when heated in the absence of oxygen. Coke, which is a high strength reducing agent, is required for conversion of iron ore into molten iron in a blast furnace. As such, it is a key element in the steelmaking process. Annual exports of Australian coking coals amount to around A$20b. Our research has extens ... More
Presented by Dr. David JENKINS on 25 Nov 2016 at 11:15