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SUMMARY:Biomedical imaging at the SYRMEP beamline of Elettra
DTSTART:20140521T033000Z
DTEND:20140521T040000Z
DTSTAMP:20260904T163800Z
UID:indico-contribution-12@events.synchrotron.org.au
DESCRIPTION:Speakers: Giuliana Tromba (Elettra\, Trieste)\n\nThe SYnchrotr
 on Radiation for MEdical Physics (SYRMEP) beamline at the Elettra light so
 urce in Trieste has several years of activity in the life sciences.\nThe b
 eamline is equipped with two imaging stations for users’ experiments\, w
 ith monochromatic and white beam\, and a radiological unit for mammographi
 c studies on patients.\nPhase contrast imaging in Free Propagation (FP) mo
 dality and Analyzer Based Imaging (ABI) are the most used imaging techniqu
 es. The beamline is well suited for imaging of small animals. For this pur
 pose a protocol\, based on FP microtomography (microCT)\, has been develop
 ed for the high resolution functional and morphological imaging of asthmat
 ic mice. New staining procedures have been tested to increase the image co
 ntrast and facilitate tissues differentiation. These were applied for imag
 ing of early atherosclerosis plaques formation in ApoE-deficient transgeni
 c mice\, mimicking human atherosclerosis\, and for other purposes focused 
 to image alterations in the morphology of mice brain.\nThe beamline is als
 o extensively used for imaging engineered tissues and scaffolds\, by evalu
 ating their bio-integration in terms of new bone formation and vasculariza
 tion. \nFor most of the experiments\, single distance phase retrieval algo
 rithms are applied to enhance the visibility of the different sample phase
 s prior to the quantitative analysis. \nTo address the increased users’ 
 requests for a quantitative morphological and textural sample characteriza
 tion\, Pore3D\, a software package for 3D image processing and analysis\, 
 has been developed. In the last years the tool had a widespread applicatio
 n and now is also available for external users.\nThe mammography program w
 ith patients is focused on the development of a new protocol for tomograph
 y. The implementation of an innovative CdTe detector and the optimization 
 of exam procedure with CT reconstruction algorithm are the main issues of 
 this project.\nThe talk will give an overview of the more recent results\,
  giving a glance to the future development programs and research perspecti
 ves.\n\nhttps://events.synchrotron.org.au/event/0/contributions/12/
LOCATION:Australian Synchrotron
RELATED-TO:indico-event-0@events.synchrotron.org.au
URL:https://events.synchrotron.org.au/event/0/contributions/12/
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