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    Australian Synchrotron

    19–20 Nov 2020
    ANSTO
    Australia/Melbourne timezone
    Please find the latest version of the UM2020 Program, Poster Presentations & Book of Abstracts at the bottom of the overview page

    Bettina Richen, Events

    Session

    Session 1 - Biomedicine & Health

    19 Nov 2020, 10:25
    ANSTO

    ANSTO

    Online

    Presentation materials

    There are no materials yet.

    1. 230. USING SYNCHROTRON RADIATION TO MAP THE METALLO-MAZE TO MEMORY LOSS
      Dr Mark J. Hackett (School of Molecular and Life Sciences, Curtin University)
      19/11/2020, 10:30
      Biomedicine and Health
      Oral

      Transition metals such as Fe, Cu, Zn are essential for brain function, because they enable energy production, metabolism, and neurotransmitter synthesis. Disturbed brain metal homeostasis has been observed in the ageing and degenerating brain (e.g., Alzheimer’s disease). Elevated levels of Fe, Cu, Zn are frequently observed in to spatially associate with markers of brain pathology (e.g....

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    2. 176. Spectroscopic Studies of Brain Zinc Homeostasis and Its Role During Cognitive Decline and Ageing
      Ashley Hollings (Curtin University, Bentley Western Australia 6845, Australia)
      19/11/2020, 11:00
      Biomedicine and Health
      Oral

      The greatest risk factor for dementia is ageing. With no cure or effective therapies to slow progression, and with an ageing population, dementia has reached crisis levels in Australia. The content and distribution of metals such as Fe, Cu, Zn is known to change in the ageing brain (metal dis-homeostasis)(1, 2), and thus, increased understanding of the mechanistic role of metal dis-homeostasis...

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    3. 194. Towards Personalized Microbeam Radiation Therapy for Brain Cancer Treatment
      Elette Engels (University of Wollongong)
      19/11/2020, 11:20
      Biomedicine and Health
      Oral

      Brain cancer is a detrimental disease with poor long term prognosis. The most common type of brain cancer, glioblastoma, has an associated 5 year survival of only 5% in Australia [1]. New treatments are therefore highly sought after to overcome the glioblastoma resistance to radiation and chemotherapy. Microbeam Radiation Therapy (MRT) at the Imaging and Medical Beam Line (IMBL) of the...

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    4. 213. A structural and functional investigation of the periplasmic arsenate-binding protein, ArrX from Chrysiogenes arsenatis
      Ms Nilakhi Poddar
      19/11/2020, 11:40
      Biomedicine and Health
      Oral

      Arsenic is a toxic metalloid found both naturally in the environment and as a harmful pollutant generated from industrial waste waters and gold mines. Arsenic can exist in both organic and inorganic forms and in four oxidation states: arsines and methyl arsines (As3-), elemental arsenic (As0), arsenite (AsO33-) and arsenate (AsO43-). Although arsenic is toxic and hazardous to human health,...

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