T. E. Gureyev1,2,3,4, B. Arhatari5,6, A. Aminzadeh1, Ya. I. Nesterets7,4, S. T. Taba2, E. Vafa2, S. C. Mayo7, D. Thompson7,4, D. Lockie8, J. Fox3, B. Kumar3, Z. Prodanovic3, D. Hausermann5, A. Maksimenko5, C. Hall5, A. G. Peele5,6, M. Dimmock3, K. M. Pavlov9,3,4, S. Lewis2, G. Tromba10, H. M. Quiney1 and P. C. Brennan2
1 The University of Melbourne, Parkville 3010, Australia
2 The University...
Introduction:
Lung disease, including chronic respiratory conditions and thoracic cancers, is Australia’s second leading cause of death [1]. Furthermore, the current COVID-19 pandemic has acutely highlighted the importance of understanding acute respiratory distress syndrome and mechanical ventilation. Lung health is typically measured in the clinic by functional measures such as...
Background: The Winnie-muc2 mouse (C57BL/6 background) exhibits pathophysiology of inflammatory bowel disease and other organ system changes, providing an opportunity to study bone loss related to malabsorption and other factors. We hypothesised that both bone microstructure and mineralisation may differ in Winnie-muc2 mice so performed temporal studies using high-resolution...
T cells are broadly categorised by their expression of either an αβ or γδ T cell receptor (TCR). Whilst αβ T cells are comprehensively understood γδ T cells are ill-defined but are increasingly realised to be an important T cell subset that display both innate- and adaptive-like immune functions. The MHC class 1 related protein (MR1), presents bacterial vitamin B metabolites to αβ mucosal...
