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    ANBUG-AINSE Neutron Scattering Symposium, AANSS 2020

    11–13 Nov 2020
    Online Event
    Australia/Sydney timezone

    Contact

    Session

    Biological Systems

    BS
    12 Nov 2020, 14:50
    Online Event

    Online Event

    Conveners

    Biological Systems: Session 5

    • Leonie van 't Hag (Monash University)

    Presentation materials

    There are no materials yet.

    1. 132. Model membrane systems: Applications in ocular drug delivery and antimicrobial actions
      Dr Hsin-Hui Shen (Monash University)
      12/11/2020, 14:50
      Biological Systems
      Oral

      A variety of biological processes occur on cell membranes. The complexity of biological membranes makes the determination of their exact composition in a cell quite difficult. A number of simpler model membrane systems have been developed to customize the membrane size, geometry, and compositions with greater precision. In recent years, model membrane systems have been explored and...

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    2. 76. Advancements in the provision of Deuterated Lipids for Neutron applications from the National Deuteration Facility
      Dr Rao Yepuri (Australian Nuclear Science and Technology Organisation)
      12/11/2020, 15:35
      Biological Systems
      Oral

      Molecular deuteration significantly increases the options for structure-function investigations using neutron scattering and diffraction techniques. Chemical deuteration activities, where catalysed 1H/2H exchange is followed by custom chemical synthesis, have led to diverse neutron scattering and reflectometry studies previously hampered by the lack of appropriate scattering contrast in...

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    3. 37. Protein deuteration extending structural characterisations by Small Angle Neutron Scattering with Contrast Variation
      Anthony Duff (ANSTO)
      12/11/2020, 15:55
      Biological Systems
      Oral

      Protein deuteration enables unique applications of neutron scattering to the life sciences, at both low and high resolutions. In recent years, the National Deuteration Facility at ANSTO have developed and published a robust and efficient method of recombinant protein deuteration.[1] Utilising this method enables us to routinely collaborate with life scientists by removing the difficulty of...

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    4. 7. Resolving the DNA interaction of the MexR antibiotics resistance regulatory protein
      Francesca Caporaletti (Linkopings universitiet & institut Laue Langevin)
      12/11/2020, 16:15
      Biological Systems
      Oral

      Small Angle scattering is a powerful tool for analysing the shape and conformational changes of macromolecules; in particular, protein-DNA complexes need to be highly dynamic in order to be able to respond to external factors for the regulation.
      Acquired multidrug resistance (MDR) in pathogenic microbials is a worldwide threat to human health. Several MarR–like proteins regulate the expression...

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