Conveners
Biological Systems: Session 5
- Leonie van 't Hag (Monash University)
A variety of biological processes occur on cell membranes. The complexity of biological membranes makes the determination of their exact composition in a cell quite difficult. A number of simpler model membrane systems have been developed to customize the membrane size, geometry, and compositions with greater precision. In recent years, model membrane systems have been explored and...
Molecular deuteration significantly increases the options for structure-function investigations using neutron scattering and diffraction techniques. Chemical deuteration activities, where catalysed 1H/2H exchange is followed by custom chemical synthesis, have led to diverse neutron scattering and reflectometry studies previously hampered by the lack of appropriate scattering contrast in...
Protein deuteration enables unique applications of neutron scattering to the life sciences, at both low and high resolutions. In recent years, the National Deuteration Facility at ANSTO have developed and published a robust and efficient method of recombinant protein deuteration.[1] Utilising this method enables us to routinely collaborate with life scientists by removing the difficulty of...
Small Angle scattering is a powerful tool for analysing the shape and conformational changes of macromolecules; in particular, protein-DNA complexes need to be highly dynamic in order to be able to respond to external factors for the regulation.
Acquired multidrug resistance (MDR) in pathogenic microbials is a worldwide threat to human health. Several MarR–like proteins regulate the expression...
