User Meeting 2018

Session

Parallel Session 2

22 Nov 2018, 11:15

Australian Synchrotron

Conveners

Parallel Session 2: Biological Systems 1 - Sponsored by Curtin University

• Hannah Wells (Massey University)

111. It’s a living breathing moving thing: advances in functional X-ray imaging of respiratory system health for Cystic Fibrosis.

Dr David Parsons (Univ of Adelaide / Women's and Children's Hospital)

22/11/2018, 11:15

Biological Systems

Oral

The absence of non-invasive measurements of detailed lung and airway function has greatly limited respiratory system health and disease management in medicine. Recent developments in synchrotron phase-contrast imaging in live animal models has enabled significant advances in measurement of physiological stability and change airways and lungs. Beginning at SPring-8, and paralleled later at the...

92. Correlative synchrotron infrared spectroscopy and super-resolution fluorescence microscopy for the detection of cellular DNA damage

Dr Donna Whelan (La Trobe University)

22/11/2018, 11:45

Biological Systems

Oral

Single molecule localization microscopy (SMLM) and Synchrotron Fourier transform infrared (S-FTIR) spectroscopy are two techniques capable of elucidating unique and valuable detail and are especially suited for interrogation of biological samples. SMLM provides images of the structures and distributions of targeted biomolecules at spatial resolutions up to an order of magnitude better than the...

126. Exploring the Spatial Distribution of Chemical Species within Latent Fingermarks using Infrared Microscopy

Rhiannon Boseley (Curtin University)

22/11/2018, 12:00

Biological Systems

Oral

The successful recovery of latent fingermarks is a valuable tool in crime scene investigations to establish connections between suspects, objects and locations. The chemical composition of fingermark residue is a complex mixture of aqueous (eccrine fraction) and lipid (sebaceous fraction) secretions with contaminants such as food and cosmetic residues. By visualising the relative abundance and...

49. Investigating Sulfur Speciation in Biological Samples Using Medium Energy X-rays

Mark John Hackett (Curtin Univeristy)

22/11/2018, 12:15

Biological Systems

The medium energy x-ray range that spans ~2-5 keV covers the K-edge of important biological elements P and S, as well as important biological ions, Cl-, K+, Ca2+. This energy range fills the “gap” between energies typically accessed at soft x-ray or hard x-ray beamlines, The energy range is also referred to as the “tender” or “squishy” x-ray range, but regardless the name, this energy range is...

14. Localised Synchrotron Radiation In Mice Induces Persistent Systemic Genotoxic Events Mediated By The Functional Immune System

Olga Martin (Peter MacCallum Cancer Centre)

22/11/2018, 12:30

Biological Systems

Oral

The discovery of the radiation-induced bystander effect (RIBE) (1) has expanded knowledge of radiobiological mechanisms beyond the scope of the central dogma of radiation biology, i.e. that only cells that absorbed a dose of ionising radiation (IR) are affected and the response is dose-dependent. The RIBE is now a well-established phe-nomenon comprising cyto- and genotoxic effects in...