Conveners
Biological Systems
- Nathan Cowieson (Australian Synchrotron)
Dr
Karagiannis Tom
(Baker IDI Heart and Diabetes Institute)
20/11/2014, 13:30
Biological Systems
Oral
Phototherapy is a well-established therapeutic strategy in dermatology, particularly for the treatment of psoriasis and cutaneous T-cell lymphoma. Treatment may either rely on the cytotoxic effect of light of a particular wavelength (e.g. UVB and narrowband UVB) or may require the use of a sensitizer (e.g. psoralens with UVA). We have developed iodinated DNA minor groove binding...
Ms
Donna Whelan
(Monash University)
20/11/2014, 14:00
Biological Systems
Oral
Synchrotron Fourier transform infrared (SFTIR) spectroscopy provides the best available signal-to-noise which allows for fast, sensitive detection of the holistic biochemistry of single live cells. Recently developed super-resolution fluorescence microscopy (SRFM) techniques based on single molecule emissions can yield an order of magnitude improvement in spatial resolution in the imaging of...
Prof.
Anthony White
(University of Melbourne)
20/11/2014, 14:20
Biological Systems
Oral
A hallmark of neurodegeneration is a failure of homeostatic mechanisms controlling the concentration and distribution of biometals. A major roadblock to understanding the impact of altered biometal homeostasis in neurodegenerative disease is the lack of specific and sensitive techniques capable of providing quantitative subcellular information on biometals in situ. Advances in X-ray...
Dr
Mark Tobin
(Australian Synchrotron)
20/11/2014, 14:40
Biological Systems
Oral
Developments to enable infrared microspectroscopy to extend beyond the far field diffraction limit are being undertaken at several accelerator facilities worldwide. These include the CLIO Free Electron Laser (Paris, France), LNLS (Campinas, Brazil), and the ALS infrared beamline (Berkeley, USA). Without such developments, the spatial resolution in the mid-IR is typically 3 to 5 microns. Two...
