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Mr Muhammad Salman Maqbool (La Trobe University)20/11/2014, 17:30ImagingPosterNanodiamonds with nitrogen vacancy (N-V) centres have been shown to be useful for applications involving cellular tracking in vivo at the molecular level[1]. The sustained fluorescence of these nanodiamonds is related to their structure, and is supposed to be influenced by the strain distribution inside the crystals. In the present work, Bragg coherent diffractive imaging (BCDI) has been...Go to contribution page
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Ms Julia Wind (University of Sydney)20/11/2014, 17:30Advanced MaterialsPosterMaterials that exhibit significant mobility of different types of charge carriers have potential applications as fuel-cell membranes, electrodes, batteries and sensors. A thorough understanding of the fundamental atomic-scale mechanisms of the conduction processes in these materials is necessary to identify ways in which their local chemistry and structure can be modified to lower activation...Go to contribution page
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Dr Adrian Hawley (Australian Synchrotron)20/11/2014, 17:30Biological SystemsPosterIn the body, triglyceride oils are digested into amphiphilic fatty acid and monoglyceride. These products subsequently self-assemble into a range of structures, including liquid crystal phases.1,2 It is hoped that understanding their digestion and self-assembly processes offers new opportunities for lipophilic drug delivery. Previous studies using small angle scattering and cryo-TEM have...Go to contribution page
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111. A combined XAS and TEM study on functional cobalt oxide catalysts for water oxidation catalysisMs Hannah King (James Cook University)20/11/2014, 17:30Earth and EnvironmentPosterOne of the biggest challenges of the 21st century is to develop methods of producing cheap, carbon-neutral, clean energy.(1) The Sun is a forefront renewable energy source, however current solar technologies are limited by the Sun’s diurnal nature. To become a viable future technology, solar energy systems will need to efficiently convert sunlight into energy, and then provide a method of...Go to contribution page
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Dr Iwan Cornelius (Imaging and Medical Beamline, Australian Synchrotron, Clayton, Victoria, Australia)20/11/2014, 17:30Radiotherapy and RadiobiologyPosterSpectroscopy has the potential to be a powerful tool for the quality assurance (QA) of radiotherapy beams; however, direct measurement using spectroscopy detectors is confounded by pulse pile up effects. This is particularly significant for high dose rate, synchrotron based stereotactic radiotherapy modalities such as microbeam radiation therapy (MRT). We herein investigate a Compton...Go to contribution page
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Mr Nader Afshar (Controls Engineer)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterReliable, robust, and predictable control of motion axes is a key component to any synchrotron beamline. To this end, new motion controls hardware (Geo-Brick-LV-GBLV, Delta-Tau-UK) was recently introduced at the XAS, IMBL, SXR and XFM Beamlines. Challenges included optimising and tuning motion axes behaviour for in-vacuum motors, closed-loop tracking axes, and scanners with velocity...Go to contribution page
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Mr Jamie Hicks (Monash University)20/11/2014, 17:30Advanced MaterialsPosterThe synthesis, structure, bonding and reactivity of molecular compounds containing unusual metal-metal bonds continues to be a topic of considerable interest. We have added to this field by utilising extremely bulky monodentate amido ligands for the stabilisation of a number of low oxidation state transition metal complexes, of which some have shown reactivity comparable to that of the...Go to contribution page
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Dr Mark Edmonds (Monash University)20/11/2014, 17:30Surface SciencePosterTopological insulators, such as Bi2Se3, are a new class of material that possess topologically protected Dirac surface states that hold great promise for next generation nano-electronic devices [1]. However, major challenges exist in realizing Bi2Se3 devices that operate in the topological regime in air. The first is that as-prepared Bi2Se3 is invariably n-type doped due to selenium vacancies...Go to contribution page
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Dr Helen Brand (Australian Synchrotron.)20/11/2014, 17:30Earth and EnvironmentPosterThe powder diffraction beamline at the Australian Synchrotron exploits the unique properties of synchrotron radiation by offering tunable wavelengths (6 keV – 30 keV) to minimise sample absorption, high flux and good S/N for increased detection limits, and high resolution to minimise peak overlap. The X-ray powder diffraction beamline produces bright, high collimated X-ray beams that, when...Go to contribution page
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Andreas Moll (Australian Synchrotron), Lauren Baird (Australian Synchrotron), Rosemary Waghorn (Australian Synchrotron)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterThe User Portal facilitates all aspects of user engagement with the synchrotron from proposal submission, down to processing data on massive and inputting subsequent publications. Ongoing development aims to enhance user experience, improve access to data and increase reporting output; for the users, the Australian Synchrotron and funding bodies.Go to contribution page
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Dr Cyril Curtain (Florey Institute of Neuroscience and Mental Health)20/11/2014, 17:30Structural BiologyPosterThe 140 residue intrinsically disordered protein -synuclein (-syn) misfolds to form fibrils that are the major constituent of the Lewy body intracellular protein inclusions and neurotoxic oligomers occurring in a number of neurodegenerative diseases, including Parkinson’s disease (PD) and dementia with Lewy bodies. Using SAXS data analysed by ensemble optimised modelling (EOM) we have been...Go to contribution page
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Prof. Feng Wang (Swinburne University of Technology), Ms Rebecca Auchettl (Swinburne University of Technology)20/11/2014, 17:30Structural BiologyPosterMethoxyphenols (MPs) are antioxidants play an important role in degenerative diseases & cancers. Methoxyphenols are found in many food products however, the molecular details of methoxyphenols are limitedly known. o-methoxyphenol (oMP), m-methoxyphenol (mMP) and p-methoxyphenol (pMP) are positional isomers of one another. The electronic structures, properties and spectra of oMP, mMP & pMP were...Go to contribution page
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Dr Ganesan Ramanathan (ARPANSA)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterCalorimetry is the most accurate method of quantifying the x-ray flux and dose in the synchrotron beam lines for medical and research applications. In calorimetry, the radiation dose absorbed results in raising the temperature of the absorbing medium which is measured accurately. Several absorbing media have been tried but graphite with relatively low specific heat and zero heat defect has...Go to contribution page
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Ms Katie H. Sizeland (Massey University)20/11/2014, 17:30Soft MatterPosterLeather is a complex biomaterial largely composed of collagen fibrils. As skins are processed to produce leather, chemical and physical changes take place that affect the physical properties of the material. The structural foundation of these changes at the collagen fibril level is not fully understood and formed the basis of this investigation. Synchrotron-based small-angle X-ray scattering...Go to contribution page
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Gloria Xun (Australian Synchrotron)20/11/2014, 17:30Structural BiologyPosterThe biological functions of proteins depend on the ability of the proteins to fold correctly. Misfolding/unfolding of proteins can cause formation of insoluble pathological aggregates, leading to degenerative diseases, such as Alzheimer’s and Parkinson’s [1]. Although considerable studies have been carried out on the molecular mechanism of protein aggregation, the lack of detailed information...Go to contribution page
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Prof. Michael Lerch (CMRP, UoW)20/11/2014, 17:30Radiotherapy and RadiobiologyPosterResults of quantitative evaluation and comparison of dose deposition patterns and radiobiological effects in synchrotron microbeam radiotherapy (MRT) - in particular, the inter-microbeam "valley" dose - for six beam geometries and three different in-beam dose values are presented. The X-Tream dosimeter and Gafchromic film have been used to quantitatively compare the dose distribution resulting...Go to contribution page
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Saliha Muradoglu (ANU)20/11/2014, 17:30Advanced MaterialsPosterWhen high energetic heavy ions penetrate a solid, energy is lost predominantly through inelastic collisions with the target electrons. Such interactions can leave narrow cylindrical trails of damage as the ions traverse through the material, termed ‘ion tracks’. In minerals such as apatite, track formation can occur as a result of spontaneous fission from naturally occurring uranium...Go to contribution page
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Lenneke Jong (Australian Synchrotron)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterThe Scientific Computing and IT group at the Australian Synchrotron develops software tools to support beamline science, maximise the user experience and accelerate the scientific outcomes of their beam time. Our suite of open source tools facilitate better and more streamlined data collection integrated with automatic and real-time processing, the results of which can inform decisions about...Go to contribution page
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Mr Kedar Deshmukh (Monash University)20/11/2014, 17:30Advanced MaterialsPosterThe microstructure and device physics of photovoltaic polymer blends based on the donor polymer BFS4 (a dithienyl-benzo[1,2- b:4,5-b]dithiophene / 5-fluoro-2,1,3-benzothiadiazole co-polymer) paired with the naphthalene diimide-based acceptor polymer P(NDI2OD-T2) will be presented. Efficiencies of over 4% are demonstrated, with an open circuit voltage of greater than 0.9 V achieved. Near-edge...Go to contribution page
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Dr Michael Jones (Australian Synchrotron; ARC Centre of Excellence for Advanced Molecular Imaging)20/11/2014, 17:30ImagingPosterX-ray coherent diffractive imaging provides high resolution, high sensitivity images of intact cellular specimens without the need for sectioning, staining, or tagging. Recent advances in this field allow high resolution imaged to be obtained with a fraction of the dose than otherwise possible while increasing image quality. Further advances have pushed the technique into the X-ray...Go to contribution page
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Mr Nicholas Anthony (Australian Research Council, Centre of Excellence in Advanced Molecular Imaging, La Trobe University, VIC 3086, Australia)20/11/2014, 17:30Structural BiologyPosterPtychography is a method for quantitatively determining the phase of of a samples’ complex transmission function. The technique relies upon the collection of multiple overlapping coherent diffraction patterns from laterally displaced points on the sample. The overlap of measurement points provides complementary information that significantly aids in the reconstruction of the complex wavefield...Go to contribution page
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Ms Hannah Coughlan (La Trobe University)20/11/2014, 17:30Structural BiologyPosterBragg Coherent Diffractive Imaging (BCDI) of radiation hard crystals (e.g. lead, gold) is now a relatively mature technique for characterising elastic strain fields at the nanoscale. The technique relies upon the fact that coherent diffraction from a crystal produces a continuous intensity distribution around every Bragg peak; if sampled correctly, this information can be used to reconstruct...Go to contribution page
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Mr Guido Cadenazzi (La Trobe University)20/11/2014, 17:30ImagingPosterPtychography has rapidly developed into a widespread technique for high-resolution X-ray microscopy due to improvements in image quality and the added flexibility over conventional Coherent Diffractive Imaging (CDI) techniques. These benefits are achieved via scanning the sample across a finite incident beam such that overlapping regions reinforce the solution for the sample transmission...Go to contribution page
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Dr Anton Tadich (Australian Synchrotron)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterMany of the more demanding surface science experiments at the soft x-ray beamline are often concerned with the interaction between ordered substrates of novel materials and adlayer molecules or thin films. Whilst soft x-ray spectroscopy is extremely powerful in characterizing the chemical information at such interfaces, being able to measure concomitant changes in other physical properties can...Go to contribution page
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Prof. Janice Aldrich-Wright (University of Western Sydney)20/11/2014, 17:30Biological SystemsPosterThe binding affinity of a series of square planar achiral platinum(II) compounds of the type [Pt(AL)(IL)]2+, where AL is 1,2-diaminoethane and IL are 1,10-phenanthroline (phen), 4-methyl-1,10-phenanthroline (4-Mephen), 5-methyl-1,10-phenanthroline (5-Mephen), 4,7-dimethyl-1,10-phenanthroline (47-Me2phen), 5,6-dimethyl-1,10-phenanthroline (56-Me2phen) or 3,4,7,8-tetramethyl-1,10-phenanthroline...Go to contribution page
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Dr David Turner (Monash University)20/11/2014, 17:30Advanced MaterialsPosterChiral coordination polymers, using ligands that contain large aromatic cores have been used to synthesize a series of polycatenanes and a polyrotaxane, by virtue of π interactions involving metallomacrocyclic motifs, including interpenetrated networks that have been used as stationary phases to obtain excellent enantiomeric resolution in liquid-chromatographic separations. A series of...Go to contribution page
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Mr Giang Tran (La Trobe University)20/11/2014, 17:30ImagingPosterCoherent diffractive imaging (CDI) is a powerful method for recovering the transmission function of an object from its far-field diffraction pattern using iterative algorithms [1]. Recently, it has been shown that CDI works with partially coherent beam [2]. Methods have been developed for dealing with CDI data for which the coherence properties of the illumination are unkown [3]. In this work,...Go to contribution page
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Mr Nicholas Rae (Australian Synchrotron)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterX-ray Absorption Spectroscopy is a technique for structure determination and speciation studies which is well suited to the in situ study extreme environments. Extreme environments are systems under high pressure and high temperature. These systems occur in nature when geofluids dissolve metals from large regions of host rock, and later precipitate the metals as ore deposits. Apart from...Go to contribution page
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Dr Martin de Jonge (Australian Synchrotron)20/11/2014, 17:30Biological SystemsPosterThe promise of non-destructive 3D elemental imaging using x-ray fluorescence tomography is alluring, but the technique is not widely utilised due to the extremely long scan times required for modest tasks. Accordingly, the technique is often applied to imaging of small specimens at low definition. Our first 3D demonstration on a 10-μm estuarine diatom, Cyclotella meneghiniana achieved a...Go to contribution page
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Ms sahar mirzaei (ANU)20/11/2014, 17:30Energy MaterialsPosterThe structural properties of Ge NPs synthesised by ion implantation in amorphous Si3N4 at 400 oC. A combination of conventional techniques (XRD and RBS) and synchrotron-based method have been used to investigate the properties of NPs. XRD spectra reveals poly crystallization of the matrix for samples annealed at 1100 oC and a peak related to SiGe structure. RBS study indicates diffusion of Ge...Go to contribution page
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Mr Pablo Mota Santiago (Australian National University)20/11/2014, 17:30Advanced MaterialsPosterThe photoluminescence signal of Amorphous silicon oxynitrides can be tunable by controlling their stoichiometry. The change in PL is related to defect centres and phase structures changes [1]. A coupling between the surface plasmon resonace of Au nanoparticles with these PL centres would lead to develop new optoelectronic and light source devices. To study this process we...Go to contribution page
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Ms Song Ha Nguyen (Swinburne University of Technology)20/11/2014, 17:30Soft MatterPosterSelf-assembly of molecules on highly oriented pyrolytic graphite (HOPG) to form ordered patterns have been an area of active research since it is relevant to colloidal stabilization, patterning and thin film devices. Most of the works have focused on 2D crystalline layers of the molecules absorbed onto graphite surfaces. However, more and more research has provided the significance of forming...Go to contribution page
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Dr Christopher Hall (Australian Synchrotron)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterThe use of radiochromic film for clinical dosimetry is well established, and in principle these films can provide the high spatial resolution dosimetry required for the microbeam x-ray radiotherapy research taking place on IMBL. The spatial resolution of a measurement made with the radiochromic film is typically limited by the densitometry. For broad beam illuminations (> 1 mm) the spatial...Go to contribution page
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Daryl Howard (Australian Synchrotron)20/11/2014, 17:30ImagingPosterA Tudor portrait of Henry VIII on oak dating from 1540s is currently undergoing conservation treatment. This treatment includes the removal of restoration paint layers applied prior to its acquisition by the Art Gallery of New South Wales. Conventional imaging techniques, x-radiography, infrared reflectography and ultraviolet fluorescence suggested damages underneath the restorations. These...Go to contribution page
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Ms Lauren Macreadie (Monash University)20/11/2014, 17:30Advanced MaterialsPosterThe hydrogen bonding in mixed sulfur/oxygen acceptor systems can be thoroughly investigated using the O-ethylxanthate (or O-alkyldithiocarbonate) family of anions. A series of O-ethylxanthate salts (guanidinium, methylammonium, dimethylammonium, trimethylammonium, tetramethylammonium, tetraethylammonium, and tetrapropylammonium), were structurally characterised using synchrotron X-ray...Go to contribution page
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Dr Chris Ryan (CSIRO)20/11/2014, 17:30ImagingPosterProjection of quantitative element images from fluorescence data collected on the XFM beamline of the Australian Synchrotron equipped with a Maia detector and real-time processor uses the Dynamic Analysis (DA) method in the GeoPIXE software. It uses matrix transformations to achieve least-squares fitting of pixel spectra in X-ray fluorescence imaging and tomography at up to ~3 x 10^7 events...Go to contribution page
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Mr Neamul Khansur (UNSW)20/11/2014, 17:30Advanced MaterialsPosterBismuth ferrite, BiFeO3 (BF) is a multiferroic ceramic familiar for the existence of both strong ferroelectric and magnetic ordering at room temperature. In addition to the multiferroicity, the remarkably high Curie temperature (Tc ) and spontaneous polarization (Ps ) of BF has made it an attractive candidate to replace lead-based Pb(Zr,Ti)O3 for...Go to contribution page
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Ms Madeleine Dupont (University of Newcastle)20/11/2014, 17:30Energy MaterialsPosterManganese dioxide is used in many electrochemical applications including catalysis, batteries and electrochemical capacitors. Thin film manganese dioxide electrodes prepared by electrodeposition have been shown to have extremely high capacitive performance [1]. This is due to manganese dioxide thin films having low resistance and high surface area. However, these properties diminish markedly...Go to contribution page
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Dr Evan Robertson (La Trobe University)20/11/2014, 17:30Earth and EnvironmentPosterWater is both an important and interesting molecular system that needs to be well understood because it exists in so many fields of research, and more often than not its presence can be undesired. The ice particles in both our own atmosphere, and the ISM, predominantly exist as either small ice particles or silicate dust grains coated with ice which can act as a reaction medium for producing...Go to contribution page
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Mr Mahmut Ruzi (Latrobe University)20/11/2014, 17:30Earth and EnvironmentPosterIce plays an important role in the atmosphere of earth and the interstellar medium through interaction with radiation and hosting chemical reactions. Ice aerosols in the troposphere scatter and absorb radiation from sun and thus have substantial influence on the temperature of earth. Understanding ice’s behaviour is believed to be essential for predicting the future of earth. Due to...Go to contribution page
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Mrs Huda Alkhaldi (ANU)20/11/2014, 17:30Advanced MaterialsPosterIon irradiation of crystalline germanium (c-Ge) results in the formation of a porous surface, and sometimes buried porous layer. The controlled fabrication of such porous structures has potential applications in lighting, gas detection and catalytic applications. In the present work, we employ a combination of complimentary characterisation techniques to better understand the...Go to contribution page
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Mr Pablo Mota Santiago (Australian National University)20/11/2014, 17:30Advanced MaterialsPosterAmorphous silicon oxynitrides (SiOxNy) are commonly used as barrier material due to their interesting mechanical and chemical properties. However, their application as gradient-index materials makes them also suitable candidates for the synthesis of nanostructures [1]. Here, we present direct evidence for the formation of ion tracks in 1-micron-thick...Go to contribution page
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Dr Connie Darmanin (La Trobe)20/11/2014, 17:30Soft MatterPosterSelf-assembly lipids have been used to solve a number of G-protein coupled receptor structures to date and the mechanism behind it still remains a mystery. Here we report on two factors; lipid incubation time and protein concentration and investigate three different lipid systems; monoolein (MO), phytantriol (PT) and phytanoyl ethanomide (PE), which influenced the uptake of the Dopamine 2 long...Go to contribution page
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Dr Tamsyn Ross (Australian Synchrotron)20/11/2014, 17:30PosterAn increasing number of industrial users are looking to the SAXS/WAXS and PD beamlines for their materials characterisation needs. In recent years commercially-relevant projects from a broad range of fields, including primary industry, energy materials and mining, have met with success due to staff expertise and dedication and the high quality of the facilities.Go to contribution page
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Ms Tanita Wierenga (University of Tasmania, School of Physical Sciences - Chemistry)20/11/2014, 17:30Advanced MaterialsPosterN-Heterocyclic Carbenes (NHCs) have many advantages to their phosphine analogues and have been used for a variety of catalytic applications. Bis-NHCs in particular have been used where bidentate phosphine complexes have previously been used including polymerisation and cross coupling reactions. Our group has been interested in palladium bis-NHCs with a wide variety of different...Go to contribution page
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Dr Lars Thomsen (Australian Synchrotron)20/11/2014, 17:30Surface SciencePosterNear-edge X-ray absorption fine-structure (NEXAFS) spectroscopy is an important tool for probing the structure of conjugated polymer films used in organic electronic devices. High-performance conjugated polymers are often donor-acceptor co-polymers which feature a repeat unit with multiple functional groups. To facilitate better application of NEXAFS spectroscopy to the study of such...Go to contribution page
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Mr Safaa Ali (James Cook University)20/11/2014, 17:30Advanced MaterialsPosterPseudo-Grignard reagents1, 2, ‘‘RLnX’’ (Ln = Eu, Sm and Yb; R = Me, Ph or C6H2Me3-2, 4, 6; X = Br, I), formed by the treatment of organic halides like PhBr or PhI with rare earth metals in Lewis base solvents, can be employed to various organic or inorganic transformations3, 4. We now report the synthesis of new divalent rare earth metal formamidinate complex [Ln(Form)Br(thf)2]2 through the...Go to contribution page
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Dr Dominique Appadoo (The Australian Synchrotron)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterCurrently, lasers are being introduced to the THz/FarIR beamline at the Australian Synchrotron. This will allow some new techniques such as steady state pump probe, photolysis and pyrolysis experiments to be undertaken at the beamline. We currently have a high powered cw CO2 laser and a pulsed YAG laser. At the THz beamline, an Enclosive Flow Cooling (EFC) cell is available for use. The...Go to contribution page
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Dr Chris Glover (Australian Synchrotron)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterX-ray absorption spectroscopy (XAS) is a technique that typically challenges the performance of its monochromator. The XAS Beamline at the Australian Synchrotron utilises a commercially delivered liquid Nitrogen cooled double crystal monochromator (DCM). This DCM possesses excellent energy and beam offset stability. Some mechanical and electrical improvements have been made in-house to enhance...Go to contribution page
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Dr Kathryn Spiers (Australian Synchrotron)20/11/2014, 17:30PosterThe Australian Synchrotron is a powerful scientific tool offering state of the art techniques and is ideally positioned to provide services for the evolution and commercialization of the next generation of high-tech products. The increasing pressure to move products to market quickly has required industry to look for new approaches in their development cycle. To this end, industry is embracing...Go to contribution page
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Damia Garriga (Monash University), Marion Boudes (Monash University)20/11/2014, 17:30Structural BiologyPosterThe production of diffraction-quality crystals remains the major bottleneck in X-ray crystallography, as shown by data from the main structural biology consortia. By contrast, in certain systems, crystals grow readily in the complex environment of the cell used to express the protein, be it in the natural context or in a recombinant system for overexpression. Recent interest in these in...Go to contribution page
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Prof. Geoffrey Jameson (Massey University)20/11/2014, 17:30Structural BiologyPosterA preliminary structure of the protein Yih1 (Yeast impact homologue 1), a protein of partially characterised function, has been obtained by multi-dimensional NMR methods. The ~300-residue protein has two distinct domains of approximately 120 and 160 residues with an approximately 20-residue linker. However, no NOEs could be found involving contacts between the two domains. Solution-state SAXS...Go to contribution page
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Dr Nathan Cowieson (Australian Synchrotron)20/11/2014, 17:30Biological SystemsPosterSmall-angle x-ray scattering (SAXS) is sensitive to the size and shape of macromolecules in solution. Whilst there can be some uncertainties involved in modelling macromolecular structure directly from SAXS data, relative changes in structure can be measured with a high degree of confidence. The binding of a small-molecule ligand to a large protein in itself is generally too subtle an...Go to contribution page
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Mrs Allina Nadzri (Australian National University,)20/11/2014, 17:30Earth and EnvironmentPosterIon tracks consist of narrow (~10 nm), long (~10-100 μm) cylindrical defect regions that are generated by high-velocity heavy ions when they pass through a variety of solids. Such tracks result naturally from fission of uranium inclusions in minerals such as apatite and zircon and are used for determining the age and thermal history of geological material. This so called ‘fission track dating’...Go to contribution page
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Mr YUBIAO LI (University of South Australia)20/11/2014, 17:30Earth and EnvironmentPosterChalcopyrite (CuFeS2) is the most abundant copper-bearing mineral. The dissolution of chalcopyrite in mine waste environments is considered to contribute to the serious environmental issue of acid and metalliferous drainage (AMD) through release of toxic aqueous copper, particularly in the presence of microbes, dissolved O2, aqueous Fe3+ and pyrite, with the latter two being associated with...Go to contribution page
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Dr Alan Riboldi-Tunnicliffe (Australian Synchrotron)20/11/2014, 17:30PosterWe offer services from cloning your gene and small scale expression trials, protein purification and crystallisation trials, through to full structure determination.Go to contribution page
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Dr Grant van Riessen (La Trobe University)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterCoherent diffractive imaging is a high-resolution method capable of providing phase, chemical and magnetic sensitivity over a large field-of-view[1]. Because iterative algorithms are substituted for image-forming lenses, the technique is not limited by the difficulty of manufacturing X-ray optics. It has been widely adopted by the international synchrotron community and is quickly becoming a...Go to contribution page
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Mr Jeffrey Seow (Monash University)20/11/2014, 17:30Structural BiologyPosterMerozoite surface protein 2 (MSP2) is an unstructured protein of the Plasmodium falciparum merozoite. The two allelic forms of MSP2, 3D7 and FC27, differ in a central variable region which is flanked by conserved N- and C-terminal regions. Vaccine trials using 3D7-MSP2 have shown evidence of strain specific protection despite the detectable presence of conserved region antibodies. This work...Go to contribution page
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Dr Suzanne Norwood (Institute for Molecular Bioscience, The University of Queensland, St Lucia, QLD, 4072.)20/11/2014, 17:30Structural BiologyPosterRetromer is a peripheral membrane protein complex that plays a critical role in a broad range of physiological, developmental and pathological processes including Wnt signalling, toxin transport and amyloid production in Alzheimer’s disease. The mammalian retromer complex consists of a core heterotrimeric cargo recognition sub-complex (VPS26, VPS29 and VPS35) associated with a dimer of...Go to contribution page
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Mr Ruixing Feng (Australian National University)20/11/2014, 17:30Advanced MaterialsPosterGe has been considered as a potential alternative material for silicon in fabricating future advanced CMOS devices due to its high hole mobility and low dopant activation temperature. Here we study the effect of In concentration on the structural and electrical properties of Ge with or without C co-implantation. By using extended x-ray absorption fine structure and x-ray absorption near-edge...Go to contribution page
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Dr Susanne Feil (svi)20/11/2014, 17:30Structural BiologyPosterCholesterol-dependent cytolysins (CDCs) constitute a family of bacterial toxins that form pores in many cell types. CDCs are secreted as water-soluble monomers, bind to cholesterol-rich membranes, oligomerise and insert into cell membranes. The presence of membrane cholesterol is required for the formation of large pores in cell membranes. In order to convert from a soluble monomeric protein...Go to contribution page
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Mrs shabnam Tarahi Tabrizi (macquarie university)20/11/2014, 17:30Structural BiologyPosterThe magnesium chelatase enzyme catalyses the ATP dependent insertion of Mg+ in to protoporphyrin IX(PPIX) in the first step of the chlorophyll biosynthesis pathway consists three different protein subunits ChlI ChlD and ChlH. The GUN4 protein is a regulatory subunit of Mg-chelatase that binds the chlorophyll biosynthesis intermediates, PPIX and Mg protoporphyrin(Mg-PPIX), stimulates Mg...Go to contribution page
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Dr Craig Morton (St Vincent's Institute for Medical Research)20/11/2014, 17:30Structural BiologyPosterInfection by the Hepatitis C virus (HCV) affects in the order of 150 million people world-wide with more than 300,000 dying each year from HCV-induced liver disease. The RNA-dependent RNA-polymerase of HCV, NS5b, is widely accepted as an ideal candidate for therapeutic development due to the lack of an equivalent enzymatic activity in normal human cells and the absolute dependence of viral...Go to contribution page
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Roxanne Smith (PhD student)20/11/2014, 17:30Structural BiologyPosterThe lack of antibiotic development coupled with the rapid increase of resistance to antibiotics in bacteria, has led to a situation described as an ‘alarming public health crisis’(1). Multi-drug resistant (MDR) bacteria are becoming a significant problem because some bacterial strains cannot be treated with our current strongest and last resort antibiotics. There is an urgent need to develop...Go to contribution page
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Ms sahar mirzaei (ANU)20/11/2014, 17:30Energy MaterialsPosterA uniform ion distribution of Ge+1 ions were achieved through multiple-energy/fluence implantations of Ge ions into 2μm a-Si3N4, which were grown on Si(100) substrates. Implantations were performed at temperatures of -196, 200 and 400 oC, to investigate the effect of implanting temperature on the phase of the matrix. Multiple techniques were used to characterise the evolution of the...Go to contribution page
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Jeff Crosbie (University of Melbourne)20/11/2014, 17:30Radiotherapy and RadiobiologyPosterThe aim of the project is to investigate how normal and malignant cell migration is influenced by conventional radiotherapy doses as well as by experimental treatments such as microbeam radiation therapy (MRT). Radiation-induced tumor cell migration is a recognized phenomenon that can occur when cells are sub-lethally irradiated. Our group previously demonstrated that tumor cells showed...Go to contribution page
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Bruce Cowie (Australian Synchrotron.)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterThe soft X-ray beam line has fully implemented a series of reference materials that can be placed into the X-ray beam at the same time as a sample is recorded with NEXAFS. This allows a direct cross check against a calibrated photon energy for every spectrum. All the measured reference spectra are presented here in time this will be transparently integrated into the user data takingGo to contribution page
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Dr Stephen Harrop (Australian Synchrotron)20/11/2014, 17:30Beamlines, Instrumentation and TechniquesPosterThe MX1 and MX2 beamlines at the Australian Synchrotron are sophisticated machines for the collection of single crystal X-ray diffraction data. The two stations serve a diverse community of researchers in the structural sciences, from mineralogy to virology. Here we look 'under the hood' at the technologies that bind the individual beamline components together into a highly automated data...Go to contribution page
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Dr Helen Brand (Australian Synchrotron.)20/11/2014, 17:30Earth and EnvironmentPosterJarosites and related minerals are of great interest to a range of mineral processing and research applications. In some settings jarosite formation is encouraged, In other environments jarosite formation can hinder the desired reaction. Jarosites are a major component of acidic soils and are present in significant amounts in acid mine drainage environments. There has been a recent resurgence...Go to contribution page
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Ms Tingting SONG (RMIT University)20/11/2014, 17:30Advanced MaterialsPosterDealloying, used to fabricate nanoporous metals, is a process where less noble components (e.g. Al) in the precursor (e.g. AlCu) are dissolved, leaving the nobler elements (e.g. Cu) to form a nanoporous structure. The three-dimensionally nanoporous Cu is desired in lithium-ion batteries as current collectors, which has a unique advantage in providing large surface area for active materials and...Go to contribution page
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Mr Wenchao Huang (Monash University)20/11/2014, 17:30Energy MaterialsPosterOrganic solar cells are a next generation photovoltaic technology with the potential for a low cost of manufacturing and printing on flexible substrates. The efficiency of organic solar cells has increased rapidly, recently exceeding 9% efficiency. Understanding the morphology of the active layer of polymer based bulk heterojunction solar cells is necessary to further improve device...Go to contribution page
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Dr Elizabeth Kyriakou (University of Melbourne)20/11/2014, 17:30Radiotherapy and RadiobiologyPosterThe radiobiology of microbeam radiation therapy (MRT) is poorly understood and this is confounded by difficulties in measuring the dose-distribution. Our investigation assesses the use of microscopy to determine the peak and valley dose in Synchrotron microbeam radiation therapy (MRT). MRT is performed using the horizontal collimator with arrays of 25µm wide x-ray beams with a pitch of 175µm....Go to contribution page
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Prof. Janice Aldrich-Wright (University of Western Sydney)20/11/2014, 17:30Biological SystemsPosterPlatinum(II) anticancer drugs, such as cisplatin and carboplatin, bind to DNA coordinately and have many limitations including poor effectiveness against many cancer cell lines, acquired resistance, cross-resistance as well as unwanted side effects. To overcome these limitations we have recently synthesised dinuclear (2,2':6',2''-terpyridine)-based complexes that are connected by thiol chains...Go to contribution page
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Mr Benjamin Pages (University of Western Sydney)20/11/2014, 17:30Biological SystemsPosterPlatinum(II) anticancer complexes incorporating 2,2'-bipyridine (bpy), 4,4'-dimethyl-2,2'-bipyridine (44Me2bpy) and 2-(2'-pyridyl)quinoxaline (2pq) as polyaromatic ligands and cyclic diamines as ancillary ligands have been synthesised and were characterised via several methods including synchrotron radiation X-ray crystallography. The crystal structure of...Go to contribution page
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Sherry Mayo (CSIRO)20/11/2014, 17:30ImagingPosterIt is now possible to collect very rapid micro-CT scans at IMBL with data collection times down to 16s or less per scan. This makes it possible to collect three-dimensional data on physical systems that are changing over time. While this provides an exciting scientific opportunity it also comes with significant challenges in terms of data storage, reconstruction and analysis. Dealing...Go to contribution page
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Dr Andrew Martin (ARC Centre for Excellence for Advanced Molecular Imaging, School of Physics, University of Melbourne)20/11/2014, 17:30ImagingPosterHolographic references can enhance the robustness of coherent diffraction imaging experiments and greatly simplify data analysis. However, to date holography has only only been possible with a limited set of special reference waves. We present a new approach to x-ay Fourier-transform holography with an almost unrestricted choice for the reference wave, opening up new avenues to optimize...Go to contribution page
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Dr Kappen Peter (Australian Synchrotron)20/11/2014, 17:30ImagingPosterMicro-X-ray computed tomography is a well established 3D imaging method that plays an important role in fields like materials science, food research, and bio-medical imaging. It is interesting to combine tomography with other techniques, such as X-ray diffraction, for assessing physical properties (density and crystallography) of materials that are heterogeneous on the micrometer scale. The...Go to contribution page
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Ms Mayanthi Goonewardanea (Swinburne)20/11/2014, 17:30Biological SystemsPosterRadiosensitizers are used in radiotherapy to enhance tumour control of radioresistant hypoxic tumours. Recent studies indicate that the formation of radical anions is a key step. Thus understanding the ionization reactions of radiosensitizers is crucial in evaluating the radiosensitization potential and in developing new and more effective drugs. The present study concentrates on the...Go to contribution page
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